Protein Alignment CG43110 and F12

DIOPT Version :10

• Sequence 1: NP_001246396.1
• Gene: CG43110 / 12798330
• FlyBaseID: FBgn0262570
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_000496.2
• Gene: F12 / 2161
• HGNCID: 3530
• Length: 615
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 73/256 - (28%)
• Similarity: 119/256 - (46%)
• Gaps: 34/256 - (13%)

  Fly    28 CGK------TPVPKIISGSNASQQSAQYMAGIFNTTHLLCGGTIIHEDFVLTVAHC----KSTQT 82
            ||:      :.:.:::.|..|.:.:..|:|.:: ..|..|.|::|...:|||.|||    .:.:.
Human   359 CGQRLRKSLSSMTRVVGGLVALRGAHPYIAALY-WGHSFCAGSLIAPCWVLTAAHCLQDRPAPED 422

  Fly    83 LFVRLGAYNINH---PTDQIRVIETIAHPQYSNSTYANDIALVKLERS-----VIFNLNIQPICI 139
            |.|.||....||   |...:.|.....|..:|..:|.:|:||::|:..     .:.:..:||:|:
Human   423 LTVVLGQERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVCL 487

  Fly   140 HLDATLGKQIRYYNAFGWG-RTRNAEQ-SDILQR-----IFVNRTNPMICHLYLGMSPDPKQICA 197
            ...|....:.......||| :...||: :..||.     :.:.|.:....|   |.|..|..:||
Human   488 PSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVH---GSSILPGMLCA 549

  Fly   198 TTDQG--DTCAGDSGGPLISKITYQGKNFDTQFGITSYGT--RECNGVGLYTDVSQYSGWI 254
            ...:|  |.|.|||||||:.:.....:....| ||.|:|:  .:.|..|:||||:.|..||
Human   550 GFLEGGTDACQGDSGGPLVCEDQAAERRLTLQ-GIISWGSGCGDRNKPGVYTDVAYYLAWI 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	71/242 (29%)
F12	NP_000496.2	FN2	41..88	CDD:128373
		EGF_CA	96..131	CDD:238011
		FN1	133..173	CDD:238018
		EGF	178..206	CDD:394967
		Kringle	217..295	CDD:395005
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	298..359		73/256 (29%)
		Tryp_SPc	373..612	CDD:238113	71/242 (29%)