Protein Alignment CG43110 and PRSS55

DIOPT Version :10

• Sequence 1: NP_001246396.1
• Gene: CG43110 / 12798330
• FlyBaseID: FBgn0262570
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: XP_047277448.1
• Gene: PRSS55 / 203074
• HGNCID: 30824
• Length: 376
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 75/281 - (26%)
• Similarity: 127/281 - (45%)
• Gaps: 56/281 - (19%)

  Fly    29 GKTPVPKIISGSNASQQSAQYMAGIFNTTHLLCGGTIIHEDFVLTVAHCKSTQTLF-----VRLG 88
            |:|...:|..|..|......:...|...:...|||:|:::.::||.|||..::.||     |.||
Human    85 GRTRYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLG 149

  Fly    89 AYNINHPTDQIR-VIETIAHPQYSNSTYANDIALVKLERSV-IFNLNIQPICIHLD---ATLGKQ 148
            ..::..|:.:|: |...|.|..:..:...|||||:.|...: :.:|.: |||:...   ||.
Human   150 TNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKV-PICLPTQPGPATW--- 210

  Fly   149 IRYYNAFGWGRT----RNAEQSDILQ------------RIFVNRTNPMICHLYLGMSPDPKQICA 197
             |.....|||:|    :|:.::|:::            ::|...|..|:|..|
Human   211 -RECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPKLTKNMLCAGY------------ 262

  Fly   198 TTDQGDTCAGDSGGPLISKITYQGKNFDTQFGITSYGTREC---NGVGLYTDVSQYSGWIANIVR 259
            ..:..|.|.|||||||:.......|.:  |.||.|:| :.|   |..|:||.:..|:.||..:.:
Human   263 KNESYDACKGDSGGPLVCTPEPGEKWY--QVGIISWG-KSCGEKNTPGIYTSLVNYNLWIEKVTQ 324

  Fly   260 -------SKQDRSVVSRRSNG 273
                   :::.|:.|.::..|
Human   325 LEGRPFNAEKRRTSVKQKPMG 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	70/249 (28%)
PRSS55	XP_047277448.1	Tryp_SPc	92..322	CDD:238113	70/249 (28%)