Protein Alignment CG43110 and Cfd

DIOPT Version :10

• Sequence 1: NP_001246396.1
• Gene: CG43110 / 12798330
• FlyBaseID: FBgn0262570
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_038487.1
• Gene: Cfd / 11537
• MGIID: 87931
• Length: 259
• Species: Mus musculus
• Alignment Length: 247
• Identity: 76/247 - (30%)
• Similarity: 123/247 - (49%)
• Gaps: 29/247 - (11%)

  Fly    28 CGKTPVPKIISGSNASQQSAQYMAGI-FNTTHLLCGGTIIHEDFVLTVAHCKSTQT----LFVRL 87
            |...|..:|:.|..|:..:..|||.: .|.|| :||||::.|.:||:.|||....|    :.|.|
Mouse    18 CAAQPRGRILGGQEAAAHARPYMASVQVNGTH-VCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLL 81

  Fly    88 GAYNINHPTDQIR---VIETIAHPQYSNSTYANDIALVKLERSVIFNLNIQPICIHLDATLGKQI 149
            ||::::.|....|   |...:.||.....:..:|:.|.||.::.....:::|:.:..:   .|::
Mouse    82 GAHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYE---DKEV 143

  Fly   150 R---YYNAFGWGRTRNA-EQSDILQRIFVNRTNPMICHL--YLGMSPDPKQICATTDQGDTCAGD 208
            .   ..:..|||...:| .:.|:|.::.|:..|...|:|  |.........:||.:::.|||.||
Mouse   144 EPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCAESNRRDTCRGD 208

  Fly   209 SGGPLISKITYQGKNFDTQFGITSYGTREC-NG--VGLYTDVSQYSGWIANI 257
            ||.||:..        |...|:.::|:|.| ||  .|:||.||.|..||.||
Mouse   209 SGSPLVCG--------DAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENI 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	72/237 (30%)
Cfd	NP_038487.1	Tryp_SPc	26..252	CDD:238113	72/237 (30%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		1/3 (33%)