Protein Alignment CG43110 and PRSS21

DIOPT Version :10

• Sequence 1: NP_001246396.1
• Gene: CG43110 / 12798330
• FlyBaseID: FBgn0262570
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 80/275 - (29%)
• Similarity: 113/275 - (41%)
• Gaps: 58/275 - (21%)

  Fly    24 LKQPCGKTPV-PKIISGSNASQQSAQYMAGIFNTTHLLCGGTIIHEDFVLTVAHCKSTQT----- 82
            |..|||:..: .:|:.|.:|......:...:......:||.:::...:.||.|||..|.:
Human    29 LSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSDP 93

  Fly    83 --------------LFVRLGAYNINHPTDQIRVIETIAHPQY-SNSTYANDIALVKLERSVIFNL 132
                          .|..|.||...:....|.:     .|:| .||.|  |||||||...|.:..
Human    94 SGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYL-----SPRYLGNSPY--DIALVKLSAPVTYTK 151

  Fly   133 NIQPICIHLDATLGKQIRYYN-----AFGWGRTRNAE---QSDILQRIFVNRTNPMIC-HLYLGM 188
            :|||||:.     .....:.|     ..|||..:..|   ....||.:.|...|..:| ||:|..
Human   152 HIQPICLQ-----ASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKY 211

  Fly   189 S--PD--PKQICATTDQG--DTCAGDSGGPLISKITYQGKN-FDTQFGITSYGTREC---NGVGL 243
            |  .|  ...:||...||  |.|.|||||||..     .|| ...|.|:.|:|. .|   |..|:
Human   212 SFRKDIFGDMVCAGNAQGGKDACFGDSGGPLAC-----NKNGLWYQIGVVSWGV-GCGRPNRPGV 270

  Fly   244 YTDVSQYSGWIANIV 258
            ||::|.:..||..::
Human   271 YTNISHHFEWIQKLM 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	76/259 (29%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	76/258 (29%)