DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43235 and CPB2

DIOPT Version :9

Sequence 1:	NP_001245931.1	Gene:	CG43235 / 12798301	FlyBaseID:	FBgn0262880	Length:	103	Species:	Drosophila melanogaster
Sequence 2:	NP_001863.3	Gene:	CPB2 / 1361	HGNCID:	2300	Length:	423	Species:	Homo sapiens

Alignment Length:	86	Identity:	22/86 - (25%)
Similarity:	36/86 - (41%)	Gaps:	12/86 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 SYENYSVYKVFIKTRSDQQVIDGLLKDTDNYN--LWH---RGLNV----VHIMVSPVEKDSFLAV 81
            ::::..|.....:|....||:..|   |..|.  ||.   ..|.|    ||..|:..:.|:..|.
Human    22 AFQSGQVLAALPRTSRQVQVLQNL---TTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKAH 83

  Fly    82 MQKENIVVEVLIKNVQTLIDR 102
            :....|...||:.:|:.||.:
Human    84 LNVSGIPCSVLLADVEDLIQQ 104

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43235	NP_001245931.1	Propep_M14	34..102	CDD:280416	21/76 (28%)
CPB2	NP_001863.3	Propep_M14	33..104	CDD:280416	21/73 (29%)
		M14_CPB2	119..420	CDD:199868
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:P00730	181..184
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:P00730	256..257
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:P00730	311..312
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.900