DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43125 and MP1

DIOPT Version :9

Sequence 1:	NP_001247344.1	Gene:	CG43125 / 12798281	FlyBaseID:	FBgn0262588	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	NP_001303421.1	Gene:	MP1 / 40541	FlyBaseID:	FBgn0027930	Length:	400	Species:	Drosophila melanogaster

Alignment Length:	287	Identity:	74/287 - (25%)
Similarity:	111/287 - (38%)	Gaps:	94/287 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 NCGKS----------SVFSPAPWLVKIRPELSSNIT---CTGTLINERFVLTAASCI-----DYQ 72
            |||::          :.....||:..|......|:.   |.|:|||.|:|||||.|:     |:
  Fly   129 NCGENFGDRVVGGNETTKREFPWMALIEYTKPGNVKGHHCGGSLINHRYVLTAAHCVSAIPSDW- 192

  Fly    73 TELI-VRLGEIDG------TLQNSSKLQYEEIY----VARALIHRSYSSESH-QYN-IALLRLKT 124
             ||. |||||.|.      |:..:.:....|.|    |...:.|..|...|. |.| ||||||:.
  Fly   193 -ELTGVRLGEWDASTNPDCTVGKNGRRDCNEPYVDYPVEERIPHPQYPGNSRDQLNDIALLRLRD 256

  Fly   125 SVVYKKNIQPICI--------DVNVGK-----------------------VPKAPTFEIE----- 153
            .|.|...|.|:|:        ::.:|:                       :...||.|..
  Fly   257 EVQYSDFILPVCLPTLASQHNNIFLGRKVVVAGWGRTETNFTSNIKLKAELDTVPTSECNQRYAT 321

  Fly   154 KKKNEEPKKNKAGIMKRFLNWFLSLFGVREPRPDVILPPQPIAVGWPLTKQ--INESALFHQYGI 216
            :::....|:..||          .:.||...|.|         .|.||..:  .|.::.::..|:
  Fly   322 QRRTVTTKQMCAG----------GVEGVDSCRGD---------SGGPLLLEDYSNGNSNYYIAGV 367

  Fly   217 LSHRNS----ESKKDVYTDVMAYVNWI 239
            :|:..:    :....|||.|.||:|||
  Fly   368 VSYGPTPCGLKGWPGVYTRVEAYLNWI 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43125	NP_001247344.1	Tryp_SPc	37..>137	CDD:304450	44/120 (37%)
MP1	NP_001303421.1	CLIP	29..91	CDD:288855
		Tryp_SPc	137..394	CDD:214473	69/277 (25%)
		Tryp_SPc	138..397	CDD:238113	71/278 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463614
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940