DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43125 and CG30187

DIOPT Version :9

Sequence 1:	NP_001247344.1	Gene:	CG43125 / 12798281	FlyBaseID:	FBgn0262588	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	NP_001246475.2	Gene:	CG30187 / 246509	FlyBaseID:	FBgn0050187	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	269	Identity:	72/269 - (26%)
Similarity:	119/269 - (44%)	Gaps:	47/269 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 RLAVFALLLFY---QGSALFLEQNC----------GKSSVFSPAPWLVKIRPELSSNITCTGTLI 57
            |||...::.::   .|:::||:|.|          |.::.|..:.|:..:...  ::..|.||||
  Fly     4 RLAWIPVIFWFLKDVGASIFLDQICGINIALKITGGHNAAFQNSVWMAAVHNR--THFICGGTLI 66

  Fly    58 NERFVLTAASCIDYQTELIVRLGEIDGTLQNSSKLQYEEIYVARALIHRSYS-SESHQYNIALLR 121
            ::|||||||.||..|....|.|    |....|.....::  |..|::|.|:. ..|::.:|.||:
  Fly    67 HKRFVLTAAHCIVDQDVQSVSL----GAYNKSDPADRKD--VITAVVHSSFDVRASYENDIGLLK 125

  Fly   122 LKTSVVYKKNIQPICIDVN---VGKVPKAPTFEIEKKKNEEPKKNKAGIMKRFLNWF-------- 175
            |.:.|::...|:||||.:|   ...:....||:..........|....:....||..
  Fly   126 LSSDVIFNALIRPICIVLNKSMANHMRNMRTFKAFGWGTLRGNKTSDILQTIILNHLDREECYME 190

  Fly   176 LSLFGVREPRPDVILPPQPIA------VGWPLTKQINESALFH---QYGILS-HRNSESKKDVYT 230
            ||::    |....|....|..      .|.|||..:....:.:   |:||:| .:.|...:.|||
  Fly   191 LSVY----PSEKQICAGVPSGDTCGGDSGGPLTNDVFIQGIGNREVQFGIISVGKTSCDGQGVYT 251

  Fly   231 DVMAYVNWI 239
            |:|::.:||
  Fly   252 DLMSFADWI 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43125	NP_001247344.1	Tryp_SPc	37..>137	CDD:304450	33/100 (33%)
CG30187	NP_001246475.2	Tryp_SPc	35..260	CDD:214473	62/236 (26%)
CG30187	NP_001246475.2	Trypsin	316..>384	CDD:355628
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010