DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43125 and CG43742

DIOPT Version :9

Sequence 1:	NP_001247344.1	Gene:	CG43125 / 12798281	FlyBaseID:	FBgn0262588	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	NP_001261130.1	Gene:	CG43742 / 14462622	FlyBaseID:	FBgn0263999	Length:	474	Species:	Drosophila melanogaster

Alignment Length:	286	Identity:	72/286 - (25%)
Similarity:	117/286 - (40%)	Gaps:	68/286 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSATLRLAVFALLLFYQGSALFLEQNCGKSSVFSPAPWLVKIRPEL------SSNITCTGTLINE 59
            |.....|.:.|::::....|..|::||.....:..|.....|..:.      :|...|.|:||::
  Fly     1 MCCWFSLLLVAVVIYQNAFAQLLDENCKVKITYRVANGHTAITSQFMAALYNNSEFFCGGSLIHK 65

  Fly    60 RFVLTAASCIDYQTELIVRLGEIDGTLQNSS----------KLQYEEIYVARALIHRSYSSESHQ 114
            ::|||||.|:....|:.|.|||     .|.|          :|.      |:.::|.::......
  Fly    66 QYVLTAAHCVRDLDEVTVHLGE-----NNRSCPIPVCKHVLRLN------AKVILHPNFHGNIFL 119

  Fly   115 YNIALLRLKTSVVYKKNIQPICIDVNVGKVPKAPTFEIEKKKNEEP------KKNKAGIMKRFLN 173
            .:||||||:..|:::.:|:||||.::          |.....|:..      .|.:.|.:...|:
  Fly   120 NDIALLRLEREVIFEAHIRPICIILD----------EDVTSNNQNNFTAYGWGKTEHGNISDVLS 174

  Fly   174 WFLSLFGVREPRPDVILPPQPIAV------------GWPLTKQI-----NESALFHQYGILSHRN 221
             |:.|  ||.|:.........|..            |.||....     :...||   ||.|:.:
  Fly   175 -FIDL--VRLPKSMCYQNINTICAGSTSGDTCESDSGGPLIGNFVHRGKSRDILF---GITSYGD 233

  Fly   222 SESKK--DVYTDVMAYVNWITPLALD 245
            :|...  .|||||.||.:||..:.|:
  Fly   234 AECSGLFGVYTDVNAYKSWIASVVLE 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43125	NP_001247344.1	Tryp_SPc	37..>137	CDD:304450	32/115 (28%)
CG43742	NP_001261130.1	Tryp_SPc	34..253	CDD:214473	62/245 (25%)
		Tryp_SPc	35..256	CDD:238113	64/247 (26%)
		Tryp_SPc	273..467	CDD:214473
		Tryp_SPc	273..>368	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463243
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940