DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43125 and CG42694

DIOPT Version :9

Sequence 1:	NP_001247344.1	Gene:	CG43125 / 12798281	FlyBaseID:	FBgn0262588	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	NP_001188994.1	Gene:	CG42694 / 10178792	FlyBaseID:	FBgn0261584	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	272	Identity:	70/272 - (25%)
Similarity:	117/272 - (43%)	Gaps:	63/272 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VFALLLFY-----QGSALFLEQNCGK-------SSVFSP-APWLVKIRPELSSNITCTGTLINER 60
            :||.||..     ..::.||:..||.       :.:..| |.||..|  ...:::.|:|:||:::
  Fly     4 LFAWLLMLTVLQSHVNSKFLDDYCGAPISNQSITKLRQPQAGWLAHI--SNGTHVLCSGSLISKQ 66

  Fly    61 FVLTAASCIDYQTELIVRLGEIDGTLQNSSKLQYEEIYVARALIHRSYSSESHQYNIALLRLKTS 125
            |||:||.|||...:|.|:||     :.|::|..:  .|....::..|:|.:..|.:|.||:|..|
  Fly    67 FVLSAAQCIDVHGKLFVQLG-----VSNATKSPH--WYTVSNVVIPSHSGKRLQRDIGLLKLSQS 124

  Fly   126 VVYKKNIQPICIDVNVGKVPKAPTFE-------IEKKKNEE---------------------PKK 162
            |.|...:.||||.:|...:......:       :.|.||.:                     ||:
  Fly   125 VDYNDFVYPICIALNTNTLDMVKILQNFTTSAWLSKNKNPQTIVLSQLSRDRCKLNLSGNVTPKE 189

  Fly   163 NKAGIMKRFLNWFLSLFGVREPRPDVILPPQPIAVGWPLTKQINESALFHQYGILSHRNSESKKD 227
            ..|..::|..:.|:......         .|||..|..:.:::    ||...|.::.|:..|:..
  Fly   190 ICAASLQRNNSCFIDSGSAL---------TQPIIQGSNIVREM----LFGIRGYVNGRSWCSEPA 241

  Fly   228 VYTDVMAYVNWI 239
            :|.||...|.||
  Fly   242 IYIDVAECVGWI 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43125	NP_001247344.1	Tryp_SPc	37..>137	CDD:304450	34/99 (34%)
CG42694	NP_001188994.1	Tryp_SPc	46..256	CDD:304450	60/230 (26%)
		Tryp_SPc	46..253	CDD:214473	58/228 (25%)
		Tryp_SPc	319..505	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463245
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940