DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG43295 and Mrnip

DIOPT Version :9

Sequence 1:NP_001246788.1 Gene:CG43295 / 12797916 FlyBaseID:FBgn0262987 Length:167 Species:Drosophila melanogaster
Sequence 2:NP_080819.2 Gene:Mrnip / 68067 MGIID:1915317 Length:335 Species:Mus musculus


Alignment Length:232 Identity:56/232 - (24%)
Similarity:89/232 - (38%) Gaps:75/232 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 SQQIRVVQCIQCKMYQVDFVKKASTWQCKICRQKQSLLKEFFRGSAAECRVKVQHLNLERGMQEE 66
            :||.||::|..|.::|...|||:..|.||.|.:|||.::.:..||.|:||..||.|||.:|...|
Mouse     4 AQQSRVLRCCSCHIFQAHQVKKSLKWTCKACGEKQSFVRAYGEGSGADCRRHVQKLNLLQGQVSE 68

  Fly    67 CLNTGLFLTAKQQLEEEKDCQEKEENTTP-------QKKTNK-----WANYVDNTIETTQKPAAK 119
                    .:.:.:||..:..| |||..|       |:..:|     |..|:|...|..:....:
Mouse    69 --------LSLRSVEEAVNGSE-EENAGPLQAEAGSQQAPSKPLESRWLKYLDKGCEDQELDRGR 124

  Fly   120 PTKTDELS---------------------------------DEISMNFKKTRNTGPRSSKRSAEN 151
            |....:||                                 |.:..||:...:||...:::...:
Mouse   125 PALKTQLSTSAERPSSPAQPRKRKWNQRTGQPAHSLHGQGVDSVEDNFEHQDSTGLFGTEQQGTS 189

  Fly   152 ------------------MPTVTKKI---CSKWNDFL 167
                              :|:...::   .|||..||
Mouse   190 PALSTANHTRELGFPRWKLPSPVTQVNAPSSKWARFL 226

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG43295NP_001246788.1 UPF0544 7..102 CDD:292377 35/106 (33%)
MrnipNP_080819.2 UPF0544 9..107 CDD:292377 35/106 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 75..102 8/27 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 118..194 8/75 (11%)
Nuclear localization signal (NLS). /evidence=ECO:0000250|UniProtKB:Q6NTE8 145..148 0/2 (0%)
Necessary for the association with the MRN complex. /evidence=ECO:0000250|UniProtKB:Q6NTE8 203..230 6/24 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 273..335
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_2CI02
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0008397
OrthoInspector 1 1.000 - - oto92658
orthoMCL 1 0.900 - - OOG6_109425
Panther 1 1.100 - - LDO PTHR15863
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X10262
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
76.810

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