DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FCRLB and si:cabz01036006.1

DIOPT Version :9

Sequence 1:	NP_001002901.1	Gene:	FCRLB / 127943	HGNCID:	26431	Length:	426	Species:	Homo sapiens
Sequence 2:	XP_021333347.1	Gene:	si:cabz01036006.1 / 563900	ZFINID:	ZDB-GENE-160113-146	Length:	624	Species:	Danio rerio

Alignment Length:	334	Identity:	83/334 - (24%)
Similarity:	111/334 - (33%)	Gaps:	109/334 - (32%)

- Green bases have known domain annotations that are detailed below.

Human     6 ALLLLVPS-SGQAATLEKPILSLHPPWTTIFKGERVTLKCDGYHPLLLELQPISTLWYLG----- 64
            |:.|:|.| ..|||....|     .||.|  :|..|||.|        |:...||.|...
Zfish   146 AVALIVSSDEAQAAVRVSP-----QPWIT--EGHSVTLIC--------EVPGSSTGWTFSWFRDA 195

Human    65 -HL------------LLPSHKKSIEVQTPGVYRCQT-RGAPVSDPIHLSVSNDW---------LI 106
             ||            |.|:     .:|..|||.|:. ||.|.....:.|....|         |:
Zfish   196 DHLSDSSRGAGGSYTLSPA-----ALQHTGVYTCRAERGEPAYSSQNSSAQPLWVTGVSASVRLV 255

Human   107 LQVPYAPVFEGEPLVLRC--RGWYDKVVYKLHYYHDGQAVRYFHSS---------ANYTVLQARA 160
            |....:..|..:.|.|.|  .||..:              ||.|::         :...:.....
Zfish   256 LNASRSQHFSSDSLSLSCDSAGWTVR--------------RYTHTNTQDCSAQTGSTCEIQSLST 306

Human   161 SDSGRYQC---SGTMRIP----VESAPMFSAKVAVTVQELFRAPVLRVMGPREARGAALGGVVLR 218
            ||:|.|.|   ||..|.|    |...|:..|..|..|.|                |..|   .|.
Zfish   307 SDTGVYWCESESGEKRHPLNITVHDGPVILASSADPVIE----------------GETL---TLH 352

Human   219 CDTRLHPQKRDTPLQFAFYKYSRAVRRFDWGAEYTVPEPEVEELESYWC-----EAATATRSVRK 278
            |   ||.....:.|...|||....::....| |.::|.....:...|:|     |:..:..|||.
Zfish   353 C---LHRSTISSILTADFYKDGLLIQNQTTG-EMSIPTVSKSDEGFYYCKTESIESPHSWISVRA 413

Human   279 RSPWLQLPG 287
            .||.|.:.|
Zfish   414 SSPSLLIIG 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FCRLB	NP_001002901.1	Ig1_FcgammaR_like	23..100	CDD:143229	25/95 (26%)
		Ig2_FcgammaR_like	104..186	CDD:143230	24/108 (22%)
		IG_like	114..190	CDD:214653	22/93 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	400..426
si:cabz01036006.1	XP_021333347.1	Ig_2	43..151	CDD:316418	2/4 (50%)
		Ig_3	160..227	CDD:316449	22/86 (26%)
		Ig	335..>397	CDD:325142	18/84 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D277104at7742
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9806
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920