DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FCRLB and si:dkey-23a13.11

DIOPT Version :9

Sequence 1:	NP_001002901.1	Gene:	FCRLB / 127943	HGNCID:	26431	Length:	426	Species:	Homo sapiens
Sequence 2:	XP_021333780.1	Gene:	si:dkey-23a13.11 / 100006263	ZFINID:	ZDB-GENE-160113-14	Length:	1089	Species:	Danio rerio

Alignment Length:	286	Identity:	74/286 - (25%)
Similarity:	107/286 - (37%)	Gaps:	80/286 - (27%)

- Green bases have known domain annotations that are detailed below.

Human    30 PWTTIFKGERVTLKCDGYHPLLLELQPISTLWY------------LGHLLLPSHKKSI--EVQT- 79
            |...:|.||.|.|.|            :.|.:|            :.||   ||:.|:  ::.|
Zfish   227 PANPVFTGETVNLTC------------VITTYYSIWRYFWDKDDGVLHL---SHRHSVNRDILTI 276

Human    80 ------PGVYRC--QTRGAPVSDPIHLSVSNDWLILQ---------VPYAPVFEGEPLVLRCRGW 127
                  .|.|.|  :..|..||.....:|   :||::         .|.:.||.||...|:|...
Zfish   277 RAAESDQGQYWCWGEIYGRSVSTQSSTAV---YLIVKASPRSTVTVTPDSAVFTGETFNLKCVIE 338

Human   128 YDKVVYKLHYYHDGQAVRYFHSSANYTVLQ-------ARASDSGRYQCSGTMRIPVESAPMFSAK 185
            .|...:...:|.|...|: ..|..:|||.:       |..||.|:|.|.|.  |...|.......
Zfish   339 SDHSDWTYEWYADRNRVK-LQSDGHYTVNRDTLTIRGAAESDQGQYWCKGF--IDGRSVSTQPTS 400

Human   186 VAVTVQELFRAPVLRVMGPREARGAALGG--VVLRCDTRLHPQKRDTPLQFAFYKYS-----RAV 243
            |.:||::|...|.||    .:..|.||.|  |.|.|:|.|     .|...|.:||.:     :..
Zfish   401 VYLTVKDLKPKPELR----SDPAGPALTGNTVTLTCNTDL-----STGWDFYWYKNTQESEIKTT 456

Human   244 RRFDWGAEYTVPEPEVEELESYWCEA 269
            |.    ..|::....:.:...|||.|
Zfish   457 RT----NSYSMKIDSLSDGGQYWCRA 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FCRLB	NP_001002901.1	Ig1_FcgammaR_like	23..100	CDD:143229	21/92 (23%)
		Ig2_FcgammaR_like	104..186	CDD:143230	26/97 (27%)
		IG_like	114..190	CDD:214653	24/82 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	400..426
si:dkey-23a13.11	XP_021333780.1	Ig_3	41..115	CDD:316449
		IGc2	234..288	CDD:197706	15/68 (22%)
		Ig_3	316..386	CDD:316449	20/70 (29%)
		IG_like	425..497	CDD:214653	16/63 (25%)
		Ig_2	509..601	CDD:316418
		Ig_3	610..677	CDD:316449
		Ig	785..>847	CDD:325142
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9806
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11481
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010