back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cln3 and Cln3

DIOPT Version :9

Sequence 1:	NP_001139783.1	Gene:	Cln3 / 12752	MGIID:	107537	Length:	438	Species:	Mus musculus
Sequence 2:	NP_001261999.1	Gene:	Cln3 / 39981	FlyBaseID:	FBgn0036756	Length:	422	Species:	Drosophila melanogaster

Alignment Length:	441	Identity:	180/441 - (40%)
Similarity:	262/441 - (59%)	Gaps:	50/441 - (11%)

- Green bases have known domain annotations that are detailed below.

Mouse    15 EREETDSEPQ---APRLDSRSV-----LWKNAVGFWILGLCNNFSYVVMLSAAHDILKQEQASGN 71
            :..|.:.:||   .|...|||.     ||::...:||||||||:.|||||||||||:||.
  Fly     7 QEAEAEHDPQVVVTPGDASRSSRQDRGLWRDLTSYWILGLCNNYGYVVMLSAAHDIIKQF----- 66

Mouse    72 QSHVEPGPTPTPHNSSSRFDCNSISTAAVLLADILPTLVIKLLAPLGLHLLPYSP-----RVLVS 131
                  .|......|||..:|:.:||.|:||||:||:|.:|:       |:|:.|     |:.::
  Fly    67 ------NPNDESEESSSGRNCHLVSTGAILLADVLPSLFVKI-------LMPFFPFWVNFRIALA 118

Mouse   132 GVCSAGSFVLVAFSQSVGLSLCGVVLASISSGLGEVTFLSLTAFYPSAVISWWSSGTGGAGLLGS 196
            ...||..|:||.|:.:..::|.||::.|.|||:||.|||:.::.|...|||.|||||||||::||
  Fly   119 VAFSAAGFLLVGFANAEWMALLGVIITSASSGIGETTFLAYSSRYNKNVISTWSSGTGGAGVIGS 183

Mouse   197 LSYLGLTQAGLSPQHTLLSMLGIPVLLLASYFLLLTSPE----PLDPGGENEAETAARQPLIGTE 257
            |||..|.....||:.|:|.||..|.:...:::|||..|:    |:......|...:..:||:|
  Fly   184 LSYASLRSLDFSPRDTMLIMLIFPAIEAFAFWLLLRRPQVDILPVTTVESTEVLISDEKPLVG-- 246

Mouse   258 TPESKPGASWDLSLQERWTVFKGLLWYIIPLVLVYFAEYFINQGLFELLFFRNTSLSHAQQYRWY 322
                         .:|:....|.|..|::||.||||.|||||||||||::|.:..|....||||.
  Fly   247 -------------FKEKLFYIKHLFKYMLPLCLVYFFEYFINQGLFELVYFEDIFLDKDSQYRWL 298

Mouse   323 QMLYQAGVFASRSSLQCCRIRFTWVLALLQCLNLALLLADVCLNFLPSIYLIFIIILYEGLLGGA 387
            .:.||.|||.||||:...::...|::::.|.:|:...|.:|...:.|||:::|.|:|:||||||.
  Fly   299 NVDYQIGVFISRSSVNLFQLDKIWLMSIFQFVNVVYFLTEVIWWYTPSIWIVFAIVLWEGLLGGG 363

Mouse   388 AYVNTFHNIALETSDKHREFAMEAACISDTLGISLSGVLALPLHDFLCHLP 438
            ||||||:.::.|.|.:.::|||.....||:.||:|:|.||:|:|:.:|.||
  Fly   364 AYVNTFYRMSKEISPERQQFAMAMVVQSDSYGIALAGFLAIPVHNAICGLP 414

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.