DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AgaP_AGAP003666 and RAD18

DIOPT Version :9

Sequence 1:	XP_313450.5	Gene:	AgaP_AGAP003666 / 1274343	VectorBaseID:	AGAP003666	Length:	863	Species:	Anopheles gambiae
Sequence 2:	NP_009992.1	Gene:	RAD18 / 850430	SGDID:	S000000662	Length:	487	Species:	Saccharomyces cerevisiae

Alignment Length:	342	Identity:	70/342 - (20%)
Similarity:	118/342 - (34%)	Gaps:	92/342 - (26%)

- Green bases have known domain annotations that are detailed below.

Mosquito   558 HKISSLPEATTA---QLQQFDDV--CAICYQDMTSAKITRCNHYFHGVCLRKWLYVQDRCPLC-- 615
            |:|::..:.||.   .|.|.|.:  |.||...:....:|.|.|.|..:|:|..|..|..||||
Yeast     3 HQITTASDFTTTSIPSLYQLDTLLRCHICKDFLKVPVLTPCGHTFCSLCIRTHLNNQPNCPLCLF 67

Mosquito   616 -------------HEIIMNQDGNPGDESLEEQLNNGDNVRIEPRTGRPDPSADATNNRLQNVPQQ 667
                         .|||.:.      .||...|.  |.:||      |.|:....|..:.. |:.
Yeast    68 EFRESLLRSEFLVSEIIQSY------TSLRSSLL--DALRI------PKPTPVPENEEVPG-PEN 117

Mosquito   668 AAIVQGTDQADQPPAQPLFDDRYFEEQINNISRAASASRSMVGI---------------RAGQTD 717
            ::.::...:::........||.    ||...|....|.|||..|               |:.:..
Yeast   118 SSWIELISESESDSVNAADDDL----QIVATSERKLAKRSMTDILPLSSKPSKRNFAMFRSERIK 178

Mosquito   718 AQTDASKRAPHHP-----------EEQYRDEY----------GVTMRFGARENAHLYANNPAGIA 761
            .::..:::....|           |:.:.||.          .::..|....|.|..:::...:.
Yeast   179 KKSKPNEQMAQCPICQQFYPLKALEKTHLDECLTLQSLGKKPKISTTFPTESNPHNKSSSRFKVR 243

Mosquito   762 APQ--PSSGGTTGTVDGNYPSGSNSSDGSPSSSSSSSNTEDTGSMSSGSSASSSASGTLSGLSNS 824
            .|:  .||.|.|..|| .|.:...|::.......:.::...:......||...|.:||...:
Yeast   244 TPEVDKSSCGETSHVD-KYLNSMMSAEHQRLPKINFTSMTQSQIKQKLSSLGLSTNGTRQNM--- 304

Mosquito   825 SLMSAAAISFNLRRRNH 841
                       ::|.||
Yeast   305 -----------IKRYNH 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AgaP_AGAP003666	XP_313450.5	TRC8_N	9..547	CDD:290425
		zf-rbx1	<575..616	CDD:289448	16/57 (28%)
		zf-RING_2	576..616	CDD:290367	15/56 (27%)
RAD18	NP_009992.1	RAD18	1..470	CDD:227719	70/342 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910