Protein Alignment Trc8 and Trc8

DIOPT Version :10

• Sequence 1: XP_313450.6
• Gene: Trc8 / 1274343
• VectorBaseID: AGAMI1_007446
• Length: 862
• Species: Anopheles gambiae
• Sequence 2: NP_996303.1
• Gene: Trc8 / 43476
• FlyBaseID: FBgn0039668
• Length: 809
• Species: Drosophila melanogaster
• Alignment Length: 875
• Identity: 463/875 - (52%)
• Similarity: 566/875 - (64%)
• Gaps: 143/875 - (16%)

Mosquito     4 VRTKVLGLVDVIMRVPSLFIIDEILKIGMGV-----------------PIGQPA---GQPANSSA 48
            |||||||||||:||||.:.:||||||:.||:                 |...||   ||...:|.
  Fly     3 VRTKVLGLVDVMMRVPPVMVIDEILKMDMGMQSWLYPDKDKASGALATPTEAPAVPSGQDPFTSI 67

Mosquito    49 INLDSPPVAAMLPDDDRGMQDSIEVYK------------------------FVSLAVLKFLICLF 89
            ..|.|....:.....::.::.:.|..|                        .:|...:||::|:|
  Fly    68 KELFSHMTTSAQSVLEQSIEKASEAAKTHGMLSSGFNSLMNELSKDQTLADVLSTTTVKFVLCVF 132

Mosquito    90 GAISAACVFMLWTRHLVIVYMYMVSVGLIFLSYWSNVSALSVISDSPSLLEDVLSLNMDRLLDPG 154
            ..:||||:|||||||||:|||::.|:||.|||||||||||::...|||::||::|||..||||.|
  Fly   133 AFLSAACIFMLWTRHLVMVYMFLTSLGLTFLSYWSNVSALALTERSPSMVEDLMSLNTTRLLDSG 197

Mosquito   155 GVLISILPHLLAQWLMGVIFAYIHLGPRHKIVQKALPFSFLMPLLLAMLPLPSLVLKHSPAFAAI 219
            ||::|:.|||:|||.||::|||||||||.:.||:::|..|..|:||||||||:.|::|.|..|..
  Fly   198 GVVMSLAPHLMAQWFMGMLFAYIHLGPRFEHVQRSMPIIFASPILLAMLPLPAKVVQHLPVVAVF 262

Mosquito   220 LPLVLSKIALWSSSFDVVKTILSGYQHARNFASNFGIATLIENEWQRLNVPCVLRVFWTIRLTEH 284
            .|::|:||.|..|:.:..:|:.:|||:|.||.||||::.||||||||||||.||||||||||.:.
  Fly   263 TPIILTKITLMQSAMEASRTVYNGYQYAMNFVSNFGLSALIENEWQRLNVPNVLRVFWTIRLIQG 327

Mosquito   285 LVSLLMS-SEAPLRFAATVQSVLVSGCETLTAVLGMTSIISLICHYIGKMFQLFLLSEDYDEDKS 348
            ..:|..: |:.||......|.:||.||||:|||||||.:||:.|||||:.||.:||:.| ||:||
  Fly   328 GYALATTESDEPLDLMTATQKLLVDGCETMTAVLGMTGVISMFCHYIGRGFQWYLLTYD-DEEKS 391

Mosquito   349 IGTVSAILFYILALQTGLTSLSPDKRIVRLCRNMCLLVTALLHFLHNIVAPILMSLSAARNPSRK 413
            :|||||:|||||||||||||||||||.:|||||:|||:|||||||||||:|||||||||||||||
  Fly   392 LGTVSAVLFYILALQTGLTSLSPDKRFIRLCRNLCLLMTALLHFLHNIVSPILMSLSAARNPSRK 456

Mosquito   414 RHARALIVCAFLLIAPGSLLAVLWASHSPSTWLLAVTAFSVEVIVKVLVSLATYTLFLLDARRQT 478
            ||.|||.|||||::...|||..||:..|.||||||||||||||:||||||||||||||||||||.
  Fly   457 RHVRALSVCAFLVVLSVSLLYHLWSQQSISTWLLAVTAFSVEVVVKVLVSLATYTLFLLDARRQF 521

Mosquito   479 FWEKLDDYVYYIRAFGNSVEFCFGIFLFFNGAWILIFESEMIPIGGAIRALMMGIHAYFNIWCEA 543
            ||||||||:||:|||||||||||||.||.||||||||||.....||.|||:||.|||||||||||
  Fly   522 FWEKLDDYLYYVRAFGNSVEFCFGILLFINGAWILIFESAQNATGGGIRAIMMCIHAYFNIWCEA 586

Mosquito   544 RAGWVVFMKRRTAVHKISSLPEATTAQLQQFDDVCAICYQDMTSAKITRCNHYFHGVCLRKWLYV 608
            ||||.||||||:||||||:|||||.||||.||||||||||:|.|||||||.|:||||||||||||
  Fly   587 RAGWSVFMKRRSAVHKISALPEATPAQLQAFDDVCAICYQEMYSAKITRCRHFFHGVCLRKWLYV 651

Mosquito   609 QDRCPLCHEIIMNQDGNPGDESLEEQLNNGDNVRIEPRTGRPDPSADATNNRLQNVPQQAAIVQG 673
            ||||||||||:|..|  ..||:..|              ..|.|:|
  Fly   652 QDRCPLCHEIMMYTD--KADENAPE--------------AEPAPAA------------------- 681

Mosquito   674 TDQADQPPAQPLFDDRYFEEQINNISRAASASRSMVGIRAGQTDAQTDASKRAPHHPEEQYRDEY 738
              ||:||..      .|..:..||.:                  ||..:.:|||....||
  Fly   682 --QAEQPMR------IYPRDDANNAA------------------AQRRSPERAPVEASEQ----- 715

Mosquito   739 GVTMRFGARENAHLYANNLAGIAAPQPSSGGATGTVDGNYPSGSNSSDGSPSSSSSSSNTEDTGS 803
                                   ||..||..|..|:      |:.:......|:::........|
  Fly   716 -----------------------APATSSSSAAATI------GAEAVSAIVESAAAVGEARSLVS 751

Mosquito   804 MSSGSSASSSASGTLSGLSNSSLMSAAAIS 833
            ::|.|||:...|.  ||.|:||.|:|:|.|
  Fly   752 VASSSSATHRISA--SGSSDSSYMTASAQS 779

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trc8	XP_313450.6	None
Trc8	NP_996303.1	TRC8_N	8..590	CDD:463960	386/626 (62%)
		RING-H2_RNF139-like	619..659	CDD:438139	8/39 (21%)