Protein Alignment AgaP_AGAP003666 and hrd1

DIOPT Version :9

• Sequence 1: XP_313450.5
• Gene: AgaP_AGAP003666 / 1274343
• VectorBaseID: AGAP003666
• Length: 863
• Species: Anopheles gambiae
• Sequence 2: NP_596376.1
• Gene: hrd1 / 2539900
• PomBaseID: SPBC17D11.02c
• Length: 677
• Species: Schizosaccharomyces pombe
• Alignment Length: 702
• Identity: 137/702 - (19%)
• Similarity: 237/702 - (33%)
• Gaps: 240/702 - (34%)

Mosquito   223 VLSKIALWSSSFDVVKTILSGYQHARNFASN---------------------FGIA----TLIEN 262
            ||:.:.|:..|     .:||.|..|..:::.                     |.||    ||:..
pombe     7 VLASLVLFGLS-----VLLSLYSSANVYSATVMISQSPVHITIGLNVCLCLFFAIANALKTLLFG 66

Mosquito   263 EWQRLNVPCVLRVFWTIRLTEHLVSLLMSSEAPLRFAATVQSVLVSGCETLTAVLGMTSIISLIC 327
            ..|...:..:...|| |.|||.::::.:..||                            ||:
pombe    67 SLQTFELELLYEQFW-ITLTEIMLAITVFREA----------------------------ISI-- 100

Mosquito   328 HYIGKMFQLFLLSEDYDEDKSIGTVSAILFYILALQTGLTSLSPDKRIVRLCRNMCLLVTALLHF 392
                   ..|:|            :|.::|                  .|:..::|...|..|..
pombe   101 -------SFFML------------LSTLMF------------------ARVFHSICSFRTERLQI 128

Mosquito   393 LHNIVAPILMSLSAARNPSRKRHARALIVCAF--LLIAPGSLLAVLWASH---SPSTWLLAVTAF 452
                           :...::.|..:.:.||:  |.|...||:.:.:.|.   ..||.:|.|..|
pombe   129 ---------------QLTDQRFHIFSRLTCAYFVLSILDASLIYLCFTSEHLGDKSTRMLFVCEF 178

Mosquito   453 SVEVIVKVLVSLATYTLFLLDARR-QTFWEKLDDYVYYIRAFGNSVEFC-FGIFLFFNGAWILIF 515
            || :::.:.:..:...::|.:||. ...|::...|::       .:|.| .|:.|.   |:.|:|
pombe   179 SV-LLLNLTIEASKLCIYLYEARHLDQVWDEKSTYLF-------RLEVCRDGLRLL---AYSLLF 232

Mosquito   516 ESEMIPIGGAIRALMMGIHAYFNIWCEARAGWVVFMKRRTAVHKISSL-PEATTAQLQQFDDVCA 579
            ..:...:...|.::......:::::...|.    ..:.|.|...:::: |.||..||...|..|.
pombe   233 MYQFPYVSVPIYSIRQMYTCFYSLFRRIRE----HARFRQATRDMNAMYPTATEEQLTNSDRTCT 293

Mosquito   580 ICYQ----------------------DMTSAKITRCNHYFHGVCLRKWLYVQDRCPLCHEIIMNQ 622
            ||.:                      |||..::. |.|..|..|||.||..|..||:|...::
pombe   294 ICREEMFHPDHPPENTDEMEPLPRGLDMTPKRLP-CGHILHFHCLRNWLERQQTCPICRRSVI-- 355

Mosquito   623 DGNPGDESLEEQLNNGDNVR-IEPRTGRPDPSADATNNRLQNVPQQAAIV-------QGTDQADQ 679
                |::|....:....||| .:..|..|:|         ||.|...|:.       ||..||..
pombe   356 ----GNQSSPTGIPASPNVRATQIATQVPNP---------QNTPTTTAVPGITNSSNQGDPQAST 407

Mosquito   680 PPAQPLFDDRYFEEQINNISRAASASRSMVGIRAGQTDAQTDASKRAPHHPEEQYRDEYGVTMRF 744
            ....|..:...|.....::|   |.....:.:|.|.|......::|.|.:.:
pombe   408 FNGVPNANSSGFAAHTQDLS---SVIPRRIALRDGWTMLPIPGTRRIPTYSQ------------- 456

Mosquito   745 GARENAHLYANNPAGIAAPQPSSGGTTGTVDGNYPSGSNSSDGSPSSSSSSSN------------ 797
                          ..:...||:..|||       ..|||:.|.|.:..:|.|
pombe   457 --------------STSTTNPSATPTTG-------DPSNSTYGGPQTFPNSGNNPNFNRGIAGIV 500

Mosquito   798 -------TEDTGSMSSGSSASSSASGTLSGLSN--SSLMSAAAISFNLRRRN 840
                   :.:|.|:|:.|:.:|......|..:|  |||.:...:|..|.:.|
pombe   501 PPGWRLVSSNTQSLSTNSAMTSLYQNASSADNNLGSSLPNVVPLSRGLTQSN 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AgaP_AGAP003666	XP_313450.5	TRC8_N	9..547	CDD:290425	61/355 (17%)
		zf-rbx1	<575..616	CDD:289448	18/62 (29%)
		zf-RING_2	576..616	CDD:290367	17/61 (28%)
hrd1	NP_596376.1	HRD1	1..514	CDD:227568	125/662 (19%)
		zf-RING_2	291..351	CDD:290367	17/60 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5243
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770