Protein Alignment AgaP_AGAP003666 and rnf-145

DIOPT Version :9

• Sequence 1: XP_313450.5
• Gene: AgaP_AGAP003666 / 1274343
• VectorBaseID: AGAP003666
• Length: 863
• Species: Anopheles gambiae
• Sequence 2: NP_491382.2
• Gene: rnf-145 / 172053
• WormBaseID: WBGene00022471
• Length: 742
• Species: Caenorhabditis elegans
• Alignment Length: 712
• Identity: 167/712 - (23%)
• Similarity: 304/712 - (42%)
• Gaps: 138/712 - (19%)

Mosquito    85 LICLFGAISAACVFM-LWTRHLVIVYMYMVSVGLIFLSYWSNVSALSVISDSPSLLEDVLSLNMD 148
            :|..:..|..:.:|: |....|:.:|.:.:||.|..::|  .:||:.|..:..:..|:   |.:|
 Worm   111 IILSYFVIFISLMFLTLPLSRLIRMYSHFLSVFLFGVAY--KLSAIYVDLEMKTGEEE---LKLD 170

Mosquito   149 RL--LDPGGVLISILPHLLAQWLMGVIFAYIHLGPRHKIVQKALPFSFLMPLLLAMLPLPSLVLK 211
            .|  |:..|.      |.|||.|: |:...:.|....:..:.|||. |.:|::..|...|...||
 Worm   171 GLIKLERHGF------HFLAQMLL-VVLQSMLLEVDGEPWRVALPV-FALPIVARMCGCPMDKLK 227

Mosquito   212 HSPAFAAILPLVLSKIALWSSSFDVVKTILSGYQHARNFASNFGIATLIENEWQRLNVPCVLRVF 276
            ::..:|....::.....:...:..::|:..:..:..:......|:|..:...|::|.:..:|...
 Worm   228 NAHNYACTGTMIFIATYMLYRAPSLIKSTKTALRQIKAVFMVHGLADGVAVLWRKLRILELLTFT 292

Mosquito   277 WTIRLTEHLVSLLMSSEAPLRFAATVQSVLVSG-CETLTAVLGMTSI---ISLICHYIGKMFQLF 337
            |   :|..|:.|.:......|..:.|..:|::| .||....:.:.::   :|.:|.:|..:.:|.
 Worm   293 W---ITMFLMVLYVELIDKGRTWSEVGRILLTGVAETTNTPITLAALAVSVSYVCKWIADLTKLI 354

Mosquito   338 ----------LLSEDYDEDKSIGTVSAILFYILALQTGLTSLSPDKRIVRLCRNMCLLVTALLHF 392
                      |....|.|        |:...||.:|||...:..:::.:.|...:.::::|||..
 Worm   355 TGGTRSHGHVLAHSGYTE--------AVSVVILCIQTGFLGMQVEQKTILLALVLYIVISALLQS 411

Mosquito   393 LHNIVAPILMSLSAARNPSRKRHARALIVCAFLLIAP----GSLLAVLWASHSP-STWLLAVTAF 452
            |..|:..:|::|.::...||.||||.:.:...|::.|    .::||:|     | ..:...:.|.
 Worm   412 LFEIIEVVLLNLPSSPTASRARHARCICIALLLVVIPFFTTKTMLALL-----PIDIYTAIIIAN 471

Mosquito   453 SVEVIVKVLVSLATYTLFLLDARRQTFWEKLDDYVYYIRAFGNSVEFCFGIFLFFNGAWILIFES 517
            |..|..:.:..:..|.:.:::.:.:..||.:||..|||......:|               :..:
 Worm   472 SATVTARAIGVILKYIVLIVETKSEEPWEGIDDLTYYIDCANKGIE---------------LLAA 521

Mosquito   518 EMIPIGGAIRALMMG----------IHAYFNIWCEARAGWVVFMK-RRTAVHKISSLPEATTAQL 571
            :::.:.|.::.:.:|          .|...||: :.....|.|:| |..||..|:.|.:|...||
 Worm   522 KVVMVFGCMQVVKVGFSFATFAILLFHVIVNIY-KRLEHTVSFIKNRNAAVKNINRLSKADVVQL 585

Mosquito   572 QQFDDVCAICYQDM-TSAKITRCNHYFHGVCLRKWLYVQDRCPLCHEIIMNQDGNPGDES---LE 632
            ::.:||||||:.:| ..|:||.|.|||||.||||||.|:..||||:..:...|.:....|   |.
 Worm   586 REREDVCAICFIEMKEEARITPCKHYFHGPCLRKWLAVKMVCPLCYTYMKEDDFDSKSSSSGTLN 650

Mosquito   633 EQLNNGDNVRIEPRTGRPDPSADATNNRLQNVPQQAAIVQGTDQADQPPAQPLFD-DRYFEEQIN 696
            |...|.:...:|.....|:...:|.|                  |::.|.. :|| |..|
 Worm   651 EVQQNEEGAAVEENPENPEEQPEAPN------------------AERAPGD-MFDWDDLF----- 691

Mosquito   697 NISRAASASRSMVGIRAGQTDAQTDASKRAPHHPEEQYRDEYGVTMRFGARENAHLYANNPA 758
                         |.||.:               |.:.|:|..:   .|||:...|..:|.|
 Worm   692 -------------GFRAER---------------ETRNRNEQRI---HGARDMWPLLVDNDA 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AgaP_AGAP003666	XP_313450.5	TRC8_N	9..547	CDD:290425	102/493 (21%)
		zf-rbx1	<575..616	CDD:289448	26/41 (63%)
		zf-RING_2	576..616	CDD:290367	26/40 (65%)
rnf-145	NP_491382.2	TRC8_N	49..556	CDD:372682	102/489 (21%)
		RING-H2_RNF139_like	590..631	CDD:319390	26/40 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	86	1.000	Domainoid score	I5215
eggNOG	1	0.900	-	-		E1_COG5243
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I2951
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D302551at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto35171
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.830