DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AgaP_AGAP010356 and rnf150b

DIOPT Version :9

Sequence 1:	XP_559104.3	Gene:	AgaP_AGAP010356 / 1272683	VectorBaseID:	AGAP010356	Length:	361	Species:	Anopheles gambiae
Sequence 2:	NP_001017554.1	Gene:	rnf150b / 792211	ZFINID:	ZDB-GENE-050417-470	Length:	419	Species:	Danio rerio

Alignment Length:	290	Identity:	120/290 - (41%)
Similarity:	177/290 - (61%)	Gaps:	24/290 - (8%)

- Green bases have known domain annotations that are detailed below.

Mosquito    73 AYLNYSFTGPD-GHLIEFGSESAKYGEGRVLNRSGLLVHISNSANHSDHTGCSKQWSGTLGGTIP 136
            |::|.::..|| ..:....:|..:||| ..|.|....|....:|.|..| .|...     |...|
Zfish    42 AFVNITYVDPDTAEVRTEKTECGRYGE-HSLKREARGVLAMPAAPHDRH-ACDPS-----GRFTP 99

Mosquito   137 ERDAPWIALVRRGSCNFEDKVKHAYERGAAGIIIYN----DKNDT-KLEKMKINDKERNITAVFT 196
            .....||||:.||:|.::||::||....|:.::|:|    :.|:| .:....|:|    :.|:..
Zfish   100 RAHGAWIALISRGNCTYKDKIRHAVGHNASAVVIFNVGSSNPNETITMPHQGISD----VVAIMI 160

Mosquito   197 TNAMGRELIEILEVHRSV-VQMRIIEGSRQFRNLGNINRTSVLFVSISFIVLMIISLVWLVFYYV 260
            ....||||:.::|  |:: |.|.|..|:|..:..  ::||||:|||||||:||||||.||||||:
Zfish   161 PEPKGRELVLLME--RNITVHMHITIGTRNLQKY--VSRTSVVFVSISFIILMIISLAWLVFYYI 221

Mosquito   261 QRFRYLQTKDKQSKRLCSVAKRIIAKIPTKSIKSDDKEIDNDC--CAICIEPYKVTDVIRVLPCK 323
            |||||...:|:..:||...||:.|:::..::|:..|:|.::|.  ||:|||.||..||:|:|||:
Zfish   222 QRFRYANARDRNQRRLGDAAKKAISQLQVRTIRKGDQETESDFDNCAVCIEGYKPNDVVRILPCR 286

Mosquito   324 HEFHKVCIDPWLLEHRTCPMCKMDILKHYG 353
            |.|||.|:||||::|||||||||:|||..|
Zfish   287 HLFHKCCVDPWLVDHRTCPMCKMNILKALG 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AgaP_AGAP010356	XP_559104.3	PA_GRAIL_like	76..219	CDD:239037	43/149 (29%)
AgaP_AGAP010356	XP_559104.3	zf-RING_2	302..345	CDD:290367	29/44 (66%)
rnf150b	NP_001017554.1	PA_GRAIL_like	45..182	CDD:239037	43/149 (29%)
		UPF0233	<196..>221	CDD:299753	21/24 (88%)
		zf-RING_2	265..308	CDD:290367	28/42 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	374..419
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BHU7
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22765
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.880