DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AgaP_AGAP010356 and gol

DIOPT Version :9

Sequence 1:	XP_559104.3	Gene:	AgaP_AGAP010356 / 1272683	VectorBaseID:	AGAP010356	Length:	361	Species:	Anopheles gambiae
Sequence 2:	NP_001163300.1	Gene:	gol / 38006	FlyBaseID:	FBgn0004919	Length:	601	Species:	Drosophila melanogaster

Alignment Length:	338	Identity:	191/338 - (56%)
Similarity:	246/338 - (72%)	Gaps:	11/338 - (3%)

- Green bases have known domain annotations that are detailed below.

Mosquito    29 SLVAANSSPSHDIASLSQPTEFSNGVSSFALPAEDRMAIESSTLAYLNYSFTGPDGHLI---EFG 90
            :||||.|..:.|:....:|   .||..||: ..|||:|::....|:||:|:. ..|:::   ||.
  Fly    30 TLVAAMSIANQDLERYFRP---GNGTHSFS-GMEDRIAVDVYNYAFLNWSYV-EHGNMLCNMEFA 89

Mosquito    91 SESAKYGEGRVLNRSGLLVHISNSANHSDHTGCSKQWSGTLGGTIPERDAPWIALVRRGSCNFED 155
            .|.|:||||:|||.:|.|:||:.:.|.||...|:....||||..||::...||||||||.|.||:
  Fly    90 QEQARYGEGKVLNVTGRLIHITATDNFSDDYACTPYIRGTLGAPIPDKGETWIALVRRGRCTFEE 154

Mosquito   156 KVKHAYERGAAGIIIYNDKNDTKLEKMKINDKERNITAVFTTNAMGRELIEILEVHRSVVQMRII 220
            ||||.|::.|||:||||||...:||||:|..|.|||.||.|...:|::|...|:...:|. :.||
  Fly   155 KVKHVYQQNAAGVIIYNDKQVMQLEKMQIKGKTRNIAAVITYQNIGQDLSLTLDKGYNVT-ISII 218

Mosquito   221 EGSRQFRNLGNINRTSVLFVSISFIVLMIISLVWLVFYYVQRFRYLQTKDKQSKRLCSVAKRIIA 285
            ||.|..|.:.::|||||||||||||||||||||||:|||:|||||:|.||:||:.||||.|:.|.
  Fly   219 EGRRGVRTISSLNRTSVLFVSISFIVLMIISLVWLIFYYIQRFRYMQAKDQQSRNLCSVTKKAIM 283

Mosquito   286 KIPTKSIK-SDDKEIDNDCCAICIEPYKVTDVIRVLPCKHEFHKVCIDPWLLEHRTCPMCKMDIL 349
            |||||:.| ||:|::|:||||||||.||.||.||:|||||||||.||||||:|||||||||:|:|
  Fly   284 KIPTKTGKFSDEKDLDSDCCAICIEAYKPTDTIRILPCKHEFHKNCIDPWLIEHRTCPMCKLDVL 348

Mosquito   350 KHYGFV-VGSSSS 361
            |.||:| :||..|
  Fly   349 KFYGYVFLGSEES 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AgaP_AGAP010356	XP_559104.3	PA_GRAIL_like	76..219	CDD:239037	69/145 (48%)
AgaP_AGAP010356	XP_559104.3	zf-RING_2	302..345	CDD:290367	36/42 (86%)
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037	69/145 (48%)
		UPF0233	226..>258	CDD:299753	25/31 (81%)
		zf-RING_2	301..344	CDD:290367	36/42 (86%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H120181
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26141
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR22765
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.990