DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AgaP_AGAP010356 and SPAC57A7.09

DIOPT Version :9

Sequence 1:	XP_559104.3	Gene:	AgaP_AGAP010356 / 1272683	VectorBaseID:	AGAP010356	Length:	361	Species:	Anopheles gambiae
Sequence 2:	NP_593372.1	Gene:	SPAC57A7.09 / 2542187	PomBaseID:	SPAC57A7.09	Length:	372	Species:	Schizosaccharomyces pombe

Alignment Length:	239	Identity:	59/239 - (24%)
Similarity:	116/239 - (48%)	Gaps:	53/239 - (22%)

- Green bases have known domain annotations that are detailed below.

Mosquito   145 LVRRGSCNFEDKVKHAYERGAAGIIIYNDKNDT--KLEKM----KINDKERNITAVF-TTNAMGR 202
            ||:||.|.:.||...|...|..|:|:.::::.:  :|..|    |:::.:.:|.::| :|::...
pombe   146 LVQRGKCTYFDKALEAQRLGFKGVIVGDNRSPSSFRLHYMVAPDKVDESKVHIPSLFVSTSSYNL 210

Mosquito   203 ELIEILEVHRSVVQMRIIEGSRQFRNLGNINRTSVLFVSISFIVLMIISLVWLVFYYVQRF-RYL 266
            ...::|..:|..:::     ..:...||::....:|..|.|.|:|:.:..:     .:::| |..
pombe   211 LWSDLLHSYRQPLKL-----YAKPEELGDMFWPFLLCFSPSIIMLITVQAL-----AIRKFIRTY 265

Mosquito   267 QTKDKQSKRLCSVAKRIIAKIPTKSIK-----SDDKEIDNDC---------------------CA 305
            :||.|        .:|.|..:|:::|.     |:::||:|..                     |.
pombe   266 RTKSK--------TRRFIEDLPSRTISREGFYSEEEEIENSTQNGELVPLMDESTRRATFGVECV 322

Mosquito   306 ICIEPYKVTDVIRVLPCKHEFHKVCIDPWLLEHR-TCPMCKMDI 348
            ||:|.:...|.:..||||||||:.||..|::::| .||.|..::
pombe   323 ICLESFTKGDKVVALPCKHEFHRPCIAKWIVDYRHACPTCNTEV 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AgaP_AGAP010356	XP_559104.3	PA_GRAIL_like	76..219	CDD:239037	19/80 (24%)
AgaP_AGAP010356	XP_559104.3	zf-RING_2	302..345	CDD:290367	19/64 (30%)
SPAC57A7.09	NP_593372.1	COG5540	1..369	CDD:227827	59/239 (25%)
		Peptidases_S8_S53	<144..211	CDD:299169	17/64 (27%)
		zf-RING_2	320..362	CDD:290367	19/41 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910