Protein Alignment Socs1 and Socs16D

DIOPT Version :9

• Sequence 1: NP_001258532.1
• Gene: Socs1 / 12703
• MGIID: 1354910
• Length: 212
• Species: Mus musculus
• Sequence 2: NP_001259662.1
• Gene: Socs16D / 32760
• FlyBaseID: FBgn0030869
• Length: 1021
• Species: Drosophila melanogaster
• Alignment Length: 239
• Identity: 67/239 - (28%)
• Similarity: 107/239 - (44%)
• Gaps: 43/239 - (17%)

Mouse     4 RNQVAAD-NAISPAAEPRRRSEPSSSSSSSSPAAPVRPRPCPAVPAPA-----------PGDTHF 56
            :.|:|:: |.....||   ..||::.......:..:.|.|..|:|..|           |.:...
  Fly   766 QTQLASELNGTLITAE---ADEPNADLRKKFQSRALPPLPKKALPFTAAAYAIEAVKSEPEEVKT 827

Mouse    57 RTFRSHSDYRRITRTSAL--LDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVK 119
            ...:   :.|.:..||::  :...|:||||||...|.:.|.:||.|:|:||||...:..|:||.|
  Fly   828 NAIQ---EPRALQFTSSIEKVKDYGWYWGPLSSEAAEKVLSSEPDGSFIVRDSSDDHYIFSLSFK 889

Mouse   120 MASGPTSIRVHFQAGRFHLDGSRETF--DCLFELLEHYVA-----------------APRRM-LG 164
            :.:....:|:....|.|.. ||...|  ..:.|.:|..|.                 .|.|: |.
  Fly   890 LNNCVRHVRIEQDQGTFSF-GSYAKFKSQTITEFIEKAVEHSRSGRYLFFLHRRPEHGPMRVQLT 953

Mouse   165 APL-RQRRVRPLQELCRQRIVAAVGRENLAR-IPLNPVLRDYLS 206
            .|: |.:.|:.||.:||..|:.||.|::|.: :||...|.|||:
  Fly   954 NPVSRFKHVQSLQHMCRFVILKAVIRKDLIQTLPLPRRLLDYLN 997

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs1	NP_001258532.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55		13/62 (21%)
		Kinase inhibitory region (KIR)	56..67		0/10 (0%)
		Extended SH2 subdomain (ESS)	68..79		2/12 (17%)
		SH2_SOCS1	69..166	CDD:198245	35/118 (30%)
		SOCS	170..212	CDD:295349	16/38 (42%)
		Interaction with Elongin BC complex	174..183		4/8 (50%)
Socs16D	NP_001259662.1	SH2_SOCS7	839..937	CDD:198251	32/98 (33%)
		SOCS_SOCS7	960..1009	CDD:239710	16/38 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770