DRSC/TRiP Functional Genomics Resources

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Protein Alignment CNR2 and Rh6

DIOPT Version :9

Sequence 1:NP_001832.1 Gene:CNR2 / 1269 HGNCID:2160 Length:360 Species:Homo sapiens
Sequence 2:NP_524368.5 Gene:Rh6 / 41889 FlyBaseID:FBgn0019940 Length:369 Species:Drosophila melanogaster


Alignment Length:355 Identity:83/355 - (23%)
Similarity:144/355 - (40%) Gaps:83/355 - (23%)


- Green bases have known domain annotations that are detailed below.


Human    36 VAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGV 100
            :..:..:||.:|...|..|:|:..||..| |.||.:|:.:||.:||:.........| .:.|:|.
  Fly    50 IGFVIAILGTMSLAGNFIVMYIFTSSKGL-RTPSNMFVVNLAFSDFMMMFTMFPPVV-LNGFYGT 112

Human   101 DSKAVFLLKI-GSVTMTF-TASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSAL 163
            .....||.:: |.....| ..|:.|:.|.|.||| |:......:..||...|::.|.::|.:...
  Fly   113 WIMGPFLCELYGMFGSLFGCVSIWSMTLIAYDRY-CVIVKGMARKPLTATAAVLRLMVVWTICGA 176

Human   164 VSYLPLMGW---------TCCPRPCSELFPLIPNDYLLS-------------WLLFIAFLFSGII 206
            .:.:||.||         |.|           ..||...             |:.....|  .||
  Fly   177 WALMPLFGWNRYVPEGNMTAC-----------GTDYFAKDWWNRSYIIVYSLWVYLTPLL--TII 228

Human   207 YTYGHVL--WKAHQ----------HVASL-SGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICW 258
            ::|.|::  ..||:          :|||| :...|:.      ..::::|||.....:::....|
  Fly   229 FSYWHIMKAVAAHEKAMREQAKKMNVASLRNSEADKS------KAIEIKLAKVALTTISLWFFAW 287

Human   259 FP--------VLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYAL---RSGEIRSSAHH 312
            .|        :...|..|..:|:...|   ||..:.:|      ||::|.|   :..::......
  Fly   288 TPYTIINYAGIFESMHLSPLSTICGSV---FAKANAVC------NPIVYGLSHPKYKQVLREKMP 343

Human   313 CLAHWKKCVRGLGSEAKEEAPRSSVTETEA 342
            |||..|.   .|.|:::.:| .:.::|::|
  Fly   344 CLACGKD---DLTSDSRTQA-TAEISESQA 369

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CNR2NP_001832.1 7tmA_CB2 34..310 CDD:320463 74/321 (23%)
TM helix 1 36..60 CDD:320463 6/23 (26%)
TM helix 2 70..91 CDD:320463 5/20 (25%)
TM helix 3 107..129 CDD:320463 6/23 (26%)
TM helix 4 152..168 CDD:320463 2/15 (13%)
TM helix 5 187..210 CDD:320463 6/35 (17%)
TM helix 6 244..266 CDD:320463 4/29 (14%)
TM helix 7 278..303 CDD:320463 7/27 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 327..360 3/16 (19%)
Rh6NP_524368.5 7tmA_photoreceptors_insect 48..338 CDD:320207 74/318 (23%)
TM helix 1 50..74 CDD:320207 6/23 (26%)
TM helix 2 83..105 CDD:320207 5/21 (24%)
TM helix 3 121..143 CDD:320207 5/21 (24%)
TM helix 4 165..181 CDD:320207 2/15 (13%)
TM helix 5 209..232 CDD:320207 4/24 (17%)
TM helix 6 273..295 CDD:320207 4/21 (19%)
TM helix 7 306..331 CDD:320207 9/33 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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