Protein Alignment CNR2 and dop-4

DIOPT Version :9

• Sequence 1: NP_001832.1
• Gene: CNR2 / 1269
• HGNCID: 2160
• Length: 360
• Species: Homo sapiens
• Sequence 2: NP_508238.2
• Gene: dop-4 / 183715
• WormBaseID: WBGene00016872
• Length: 517
• Species: Caenorhabditis elegans
• Alignment Length: 472
• Identity: 87/472 - (18%)
• Similarity: 151/472 - (31%)
• Gaps: 189/472 - (40%)

Human    36 VAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVV-------------- 86
            :|:....:.||:...|..|:..:.:...||....||.| |||.||.:..|:
 Worm    45 LAIALFSICLLTVAGNCLVVIAVCTKKYLRNPTGYLII-SLAIADLIVGVIVMPMNSLFEIANHT 108

Human    87 FACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRAL 151
            :....:...|||.:|            .:..|||:.:|.:.::|||:..:.|..|:..:::.|.|
 Worm   109 WLFGLMMCDVFHAMD------------ILASTASIWNLCVISLDRYMAGQDPIGYRDKVSKRRIL 161

Human   152 VTLGIMWVLSALVSYLPLMGW-TCCPRPCSELFPLIPND--YLLSWLLFIAF---LFSGIIYTYG 210
            :.:..:|||||::|:..::.| |..|....:....:..|  ..:|:...::|   ||. |::.||
 Worm   162 MAILSVWVLSAILSFPGIIWWRTSSPHLYEDQSQCLFTDSKMYVSFSSLVSFYIPLFL-ILFAYG 225

Human   211 HVLWKAHQH------------VASLSG-------------------------------------- 225
            .|...|.:|            :...:|
 Worm   226 KVYIIATRHSKGMRMGIKTVSIKKRNGKKSNTETESILSSENEPTLRIHFGRGKQSSSSLRNSRF 290

Human   226 -----------------------------------------HQD------------RQV------ 231
                                                     |.|            |.|
 Worm   291 HARESTRLLLKQVSCKSLNDRGEHNNNNTVRQPLLRGTEGCHSDSISRSSQRNFRGRNVTIGSNC 355

Human   232 -------------------------PGMARMRLDV--------------RLAKTLGLVLAVLLIC 257
                                     |...|.:|:|              |.|:||.:|:...::|
 Worm   356 SSTLLQVDQPDRMSLSSNSQMVMTSPLSTRRKLNVREKSRQMMRYVHEQRAARTLSIVVGAFILC 420

Human   258 WFP--VLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKC 320
            |.|  |...:.....:..|:: :..|.|.:....:|||:||:||:..|.:.|.:....|.    |
 Worm   421 WTPFFVFTPLTAFCESCFSNK-ETIFTFVTWAGHLNSMLNPLIYSRFSRDFRRAFKQILT----C 480

Human   321 VRGLGSEAKEEAPRSSV 337
            .|....:...:.|.|.|
 Worm   481 QRQQKVKTAFKTPLSLV 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CNR2	NP_001832.1	7tmA_CB2	34..310	CDD:320463	81/443 (18%)
		TM helix 1	36..60	CDD:320463	5/23 (22%)
		TM helix 2	70..91	CDD:320463	9/34 (26%)
		TM helix 3	107..129	CDD:320463	4/21 (19%)
		TM helix 4	152..168	CDD:320463	6/15 (40%)
		TM helix 5	187..210	CDD:320463	6/27 (22%)
		TM helix 6	244..266	CDD:320463	8/23 (35%)
		TM helix 7	278..303	CDD:320463	9/24 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..360		3/11 (27%)
dop-4	NP_508238.2	7tm_4	53..>245	CDD:304433	50/205 (24%)
		7tm_1	59..463	CDD:278431	74/418 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910