| Sequence 1: | NP_001276633.1 | Gene: | Cflar / 12633 | MGIID: | 1336166 | Length: | 481 | Species: | Mus musculus |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001260718.1 | Gene: | Strica / 35528 | FlyBaseID: | FBgn0033051 | Length: | 527 | Species: | Drosophila melanogaster |
| Alignment Length: | 435 | Identity: | 83/435 - (19%) |
|---|---|---|---|
| Similarity: | 153/435 - (35%) | Gaps: | 162/435 - (37%) |
- Green bases have known domain annotations that are detailed below.
|
Mouse 148 LIASDQLNLLEKCLKNI------HRIDL------------------------------------- 169
Mouse 170 ---NTKIQKYTQSSQGAR--------------SNMNTLQASLPKLSIK----------YNSRLQN 207
Mouse 208 GRSKEPR---FVEYRDSQRT-----------LVKTSIQESGAFLPPHIR---EETYRMQSKPLGI 255
Mouse 256 CLIIDCIGNDTKYLQETFTSLGYHIQLFLFPKSHDITQI-VRRYASMAQHQDY-DSFACVLVSLG 318
Mouse 319 -GSQSMMGRDQV---HSGFSLDH------VKNMFTGDTCPSLRGKPKLFFIQNYE---SLGSQLE 370
Mouse 371 DSSLEVDGPSIKNVDSKPLQPRHCTTHPEADIFWSLCTADVSHLEKPSSSSSVYLQKLSQQLKQG 435
Mouse 436 RRRPLVD---LHVELMDKVYAWNSGVSSKEKYSLSLQHTLRKKLI 477 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Cflar | NP_001276633.1 | Interaction with CASP8 propeptide. /evidence=ECO:0000250|UniProtKB:O15519 | 6..307 | 40/246 (16%) | |
| Interaction with FADD. /evidence=ECO:0000250|UniProtKB:O15519 | 6..229 | 26/164 (16%) | |||
| Interaction with CASP8. /evidence=ECO:0000250|UniProtKB:O15519 | 6..200 | 16/111 (14%) | |||
| DED_c-FLIP_r1 | 6..85 | CDD:260044 | |||
| DED_c-FLIP_r2 | 96..176 | CDD:260046 | 9/73 (12%) | ||
| Interaction with TRAF1 and TRAF2. /evidence=ECO:0000250|UniProtKB:O15519 | 197..481 | 67/326 (21%) | |||
| Interaction with CASP3. /evidence=ECO:0000250|UniProtKB:O15519 | 197..436 | 58/280 (21%) | |||
| Interaction with CASP8 subunits p18 and p10. /evidence=ECO:0000250|UniProtKB:O15519 | 219..481 | 62/291 (21%) | |||
| CASc | 246..480 | CDD:214521 | 55/250 (22%) | ||
| Caspase | 265..360 | 30/106 (28%) | |||
| Interaction with CASP8. /evidence=ECO:0000250|UniProtKB:O15519 | 372..481 | 19/109 (17%) | |||
| Strica | NP_001260718.1 | CASc | 311..523 | CDD:294037 | 57/268 (21%) |
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3573 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||