Protein Alignment Ces1g and alpha-Est2

DIOPT Version :9

• Sequence 1: NP_067431.2
• Gene: Ces1g / 12623
• MGIID: 88378
• Length: 565
• Species: Mus musculus
• Sequence 2: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Alignment Length: 563
• Identity: 161/563 - (28%)
• Similarity: 242/563 - (42%)
• Gaps: 107/563 - (19%)

Mouse    15 LSLGHPSLPPVVHTVHGKVLGKYVTLEGFSQPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKH 79
            ||.||   ..::.|.:|:|.|.........:|...|.|:|:||||:|.|||..|:|.|||..|.:
  Fly    27 LSTGH---TVILDTKYGQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLN 88

Mouse    80 TTSYPPLCYQNPEAALRLAELFTNQRKIIPHKF-------SEDCLYLNIYTPADLTQNSRLPVMV 137
            .|                    ||:.|.:....       |||||:||:|..| |.....|||:|
  Fly    89 CT--------------------TNRSKPMQRNMLLGIVEGSEDCLHLNVYVKA-LKSEKPLPVIV 132

Mouse   138 WIHGGGLVIDGASTYDGVP-LAVHENVVVVVIQYRLGIWGFFSTEDE--HSRGNWGHLDQVAALH 199
            ||:|||.....||.....| ..:.:.||.|.|.|||...||.|.:|.  ...||.|..|||.||.
  Fly   133 WIYGGGFQKGEASRDIYSPDYFMKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALR 197

Mouse   200 WVQDNIANFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAIAQSSVIFNPCLFGRAARP-- 262
            |:..|||:|.|:|.::|:.|||||..||.|::.:...:.|||:||.||.     |........
  Fly   198 WISQNIAHFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSG-----CALSEWVESPD 257

Mouse   263 --LAKKIAALAGCKTTTSAAMV------HCLRQ--KTEDELLEVS-----LKMKFGTVDFLGDPR 312
              .|.::|...|.|.....|.|      .|.||  ..:.:::.:.     |...||.|.   :|.
  Fly   258 NNWAFRLAQNLGYKGDEKDADVLSFLSKVCARQIAAIDQDVINLDEVRSFLLFAFGPVI---EPY 319

Mouse   313 ESYPFLPTVIDGVLLPKAPEEILAEKSFNTVPYMVGINKHE--FG--------WIIPMFLDFPLS 367
            |:        |..::||..:::|:|...|.:|.:||.|..|  |.        |.:..|.:  :.
  Fly   320 ET--------DHCVVPKRHKDLLSEAWGNDIPVIVGGNSFEGLFSYQLVRKDPWALKNFHN--IL 374

Mouse   368 ERKLDQKTAASILWQAYPILNISEKLIPAAIEKYLGGTEDPATMTDLF--LDLIG--DIMFGVPS 428
            .|::.:.::..           .:.|:...:::.....|...:| ::|  |::..  .|......
  Fly   375 PREVRETSSLE-----------GQDLLVRRLKQLYFNNEMQESM-EMFEALNIFSHRQIWHDTHR 427

Mouse   429 VIVSRSHRDAGAPTYMYEYQY-RPSF------VSDDRPQELLGDHADEL-FSVWGAPFLKEGASE 485
            .|::|.......|||:|.:.: .|.|      |..||.:.:.  ||||| :..:.....|...|.
  Fly   428 FILARQSYAPKTPTYLYRFDFDSPHFNQFRRLVCGDRIRGVA--HADELSYLFYNIIASKLDKSS 490

Mouse   486 EEINLSKMVMKFWANFARNGNPNGE--GLPHWPEYDQKEGYLQ 526
            .|....:.::..|.:||.:||||..  |...|.....||..::
  Fly   491 MEYKTIERMVGMWTSFASSGNPNCPELGSAKWEAVQLKENAVE 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ces1g	NP_067431.2	COesterase	24..545	CDD:278561	157/554 (28%)
		Aes	<121..>239	CDD:223730	50/120 (42%)
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	154/543 (28%)
		Aes	<117..>221	CDD:223730	45/104 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832619
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.650