Protein Alignment CPT1C and CG5122

DIOPT Version :10

• Sequence 1: NP_001365411.1
• Gene: CPT1C / 126129
• HGNCID: 18540
• Length: 825
• Species: Homo sapiens
• Sequence 2: NP_609601.1
• Gene: CG5122 / 34703
• FlyBaseID: FBgn0032471
• Length: 1263
• Species: Drosophila melanogaster
• Alignment Length: 668
• Identity: 186/668 - (27%)
• Similarity: 305/668 - (45%)
• Gaps: 127/668 - (19%)

Human   171 LPRQPVPSVQDTVRKYLESVRPILSDEDFDWTAVLAQEFLRLQASLLQWYLRLKSWWASNYVSDW 235
            |.:.|...::.::..||.|:.|.|::|:......:|::|:..:.:.||..|..::....|:::..
  Fly   665 LKKFPALPLKQSIASYLSSIEPFLNEEELKVEQKVAKKFVDNEGAKLQQLLEEEAEGTDNWLTPR 729

Human   236 WEEFVYLRSRNPLMV---------------NSNYYMMAARAGNAVHALLLYRHRLNRQEIPPVRG 285
            |....||..:.||.|               .:::....|:   |::.:..::..:::.:||.|:
  Fly   730 WTRSAYLTYQAPLTVFSSPGLSFPIQEFKDTNDFLNFTAK---AIYGMCEFKQLVDQNKIPVVQ- 790

Human   286 PQWVRDGGVVLWPLGHVGPGRQLTAHGFLQTLLMGMRPLCSAQYEKIFNTTRIPGVQKDYIRHLH 350
                                             ||...|.::|:.|||.|.|.||...|.|...:
  Fly   791 ---------------------------------MGKHQLDNSQFGKIFGTVRKPGRFCDTIEQYN 822

Human   351 DSQHVAVFHRGRFFRMGTHSRN-SLLSPRALEQQFQRILDDPSPACPHE--EHLAALTAAPRGTW 412
            |:.::.|.:...:|::..:|:: :||....|....|.||:     ||.:  :|...||...|..|
  Fly   823 DADYIVVVYNNNYFKLPIYSQSGALLHAHTLRDALQDILE-----CPIKVGKHFGLLTHDNRSNW 882

Human   413 AQVRTSL--KTQAAEALEAVEGAAFFVSLD---AEPAGLTREDPAASLDAYAHALLAGRG----- 467
            |:..|.|  ....|:.:|.:|.:.|.|.||   ..|.|..|       ...||.||.|.|
  Fly   883 AEAYTVLCRPHGNADTVETIEQSLFVVCLDNCVPTPKGEER-------IVQAHQLLHGGGVRQNS 940

Human   468 HDRWFDKSFTLIVFSNGKLGLSVEHSWADCPISGHMWEFTLATECFQLGYSTDGHCKGHPDPTLP 532
            .:||.||:..|||..||..|...|||.|||.....:.:| :..:..:..|..:| |:.....|..
  Fly   941 ANRWMDKTIQLIVNPNGLAGFCYEHSPADCQPLAMLMDF-VQLKVTEPNYGCEG-CEADKKVTSN 1003

Human   533 ----QPQRLQWDLPDQIHSSISL----ALRGAKILSENVDCHVVPFSLFGKSFIRRCHLSSDSFI 589
                ||          ::..|:|    |.|..:.:...:..:|:.|..:||.||:...|:.||:|
  Fly  1004 LLKFQP----------VNECINLWLCQARRNIQRIVSQLQMNVINFECYGKCFIKAQGLNPDSYI 1058

Human   590 QIALQLAHFRDRGQFCLTYESAMTRLFLEGRTETVRSCTREACNFVRAMEDKEKTDPQCLALFRV 654
            |:||.||::...|:....||||..|:|.||||||:||.:.|:..|:.||:.::.:..:.||..:.
  Fly  1059 QMALSLAYYSMYGKIPAQYESAHLRIFHEGRTETIRSTSNESKTFLLAMQSEKASMSEKLAALQK 1123

Human   655 AVDKHQALLKAAMSGQGVDRHLFAL--YIVSRFLHLQSPFLTQ--VHSEQWQLSTSQIPVQQMHL 715
            |||.|:.|:|.|::|||:|||||.|  ..:.:.:.:...|.::  |.|..:||.|||:
  Fly  1124 AVDAHEKLIKEAINGQGIDRHLFGLQEMALEKGMPIPEFFRSKGYVRSVTFQLFTSQV------- 1181

Human   716 FDVHNYPDYVSSGGGF---GPADDHGYGVSYIFMGDGMITFHISSKKSSTKTDSHRLGQHIEDAL 777
                     .:|..||   ||....||||.| ...:..|||.||:.||..:.::.|..:.|:.:|
  Fly  1182 ---------ATSNEGFMAYGPLLSDGYGVCY-NPKESKITFAISAWKSCKEINTIRFAKAIKKSL 1236

Human   778 LDVASLF------QAGQH 789
            .|:..|.      :||:|
  Fly  1237 NDMRKLILLTGGERAGEH 1254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPT1C	NP_001365411.1	CPT_N	1..47	CDD:465132
		Carn_acyltransf	174..775	CDD:459926	179/643 (28%)
CG5122	NP_609601.1	PTZ00449	<299..668	CDD:185628	1/2 (50%)
		Carn_acyltransf	672..1234	CDD:459926	178/639 (28%)