Protein Alignment SLC5A10 and CG33124

DIOPT Version :10

• Sequence 1: XP_016879680.2
• Gene: SLC5A10 / 125206
• HGNCID: 23155
• Length: 649
• Species: Homo sapiens
• Sequence 2: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Alignment Length: 718
• Identity: 149/718 - (20%)
• Similarity: 258/718 - (35%)
• Gaps: 244/718 - (33%)

Human     8 DLHTPGTQLSVADIIVITVYFALNVAVGIW---------------------SSCRASRNTVNGYF 51
            |.:..||    .|..|......|::|:|::                     |........:|.|.
  Fly     2 DTYRFGT----VDYTVFLGVTILSIAIGLYFGWIKKTKKEMESSPADTPEISIPNFGSKKMNEYL 62

Human    52 LAGRDMTWWPIGASLFASSEGSGLFIGLAGSGAAGGLAVAG-----FEWNATYVL---------L 102
            :....:..:|:..||.||      ||        .|:|:.|     :.:...|.|         |
  Fly    63 MGSGHLKVFPVAMSLIAS------FI--------SGVAILGNPSEIYYYGTQYSLIVLAIVIQGL 113

Human   103 ALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGW 167
            |::::::|::.:.::.:..||:..|: ...||..:|:: .::.|.......::..||.::...|.
  Fly   114 AVSYIYLPVFSALQVRSSYEYLGMRF-HPLIRNIVSIM-FVIEVLLYTPFVVFVPALALNQASGL 176

Human   168 NFYLSTILTLGITALYTIAGGLAAVIYTDALQTLIMVVGAVILTIKA----------FDQIGGYG 222
            |.::..:|.:.:..:||:.|||.||::||..|.:||....|::.|.|          |:.:...|
  Fly   177 NIHMIEVLIIVVCVIYTLLGGLKAVVHTDIWQVVIMFASVVVVAILATCYITDLDDFFESLVDGG 241

Human   223 QLEAAYAQAIPSRTIANTTCHLPRTDAMHMFRDPHTGDLPWTGMTFGLTIMATWYW----CTDQV 283
            :|  .:....||..:.||.                     |:     :.|...:||    ...|.
  Fly   242 RL--IFGNINPSPYVRNTV---------------------WS-----VVIGGAFYWTSITAVHQT 278

Human   284 IVQRSLSARDLNHAKA-------GSILASYLKMLPMGLIIMPGMISRALFPGAHVYEERHQVSVS 341
            :|.|.:|..:|..|:.       |||: .|..:..:||:|.            ::|::...:|..
  Fly   279 MVHRYMSLPNLKMARTSIAFFVLGSII-FYSVLSFLGLLIF------------NMYKDCDPLSAG 330

Human   342 RTDDVGCVVPSECLRACGAEVGCSNIAYPKLVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSST 406
            :..:...:||...:::.|      :|           .|:.||.||.:..|.:|||:...||:|.
  Fly   331 QIMNNDQLVPLFVVQSVG------HI-----------YGIPGLFIAGIFGAGLSSLSVFLNSTSL 378

Human   407 LFTMDIWR---RLRPRSGERELLLVGRTGIPSTPPAPQSRLSFLLPETPPLERYLLGLVVMDLWL 468
            :...||.|   :::|  ||....::    :.:|
  Fly   379 VILQDIVRGCFKMQP--GETASAII----VKAT-------------------------------- 405

Human   469 VIVALIGVSVAWIPVLQDSNSGQLFIYMQSV---TSSLAPPVTAVFVLGVFWRRANEQGAFWGLI 530
              :.::|..|....:|.:..||.|.|.|..|   |||    ...:|.|.|....||..|...|.|
  Fly   406 --IVIMGALVFGEVLLLEKVSGILSICMSLVAIATSS----TFGIFTLAVLVPWANTVGTAVGGI 464

Human   531 AG-LVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVA---------------------- 572
            || |:.|......:.             .|..|.:|:....|:
  Fly   465 AGFLLTGWITFGSQI-------------AAASGQLHHHRLPVSVASCPGNVTARENVWVDEEQVF 516

Human   573 -LFALS-------GA--VVVAGSLLTPPPQSVQIENLTWWTLAQDVPLGTKAGDGQTPQKHAFWA 627
             ||.||       ||  |||.|||::...:...|::|.              .|..:|..|.|..
  Fly   517 PLFRLSFHWINPIGALTVVVVGSLVSLVTKPTDIKSLD--------------SDLISPVIHRFLP 567

Human   628 RVC 630
            :.|
  Fly   568 KEC 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A10	XP_016879680.2	SLC5-6-like_sbd	17..649	CDD:444915	146/709 (21%)
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	133/654 (20%)