DRSC/TRiP Functional Genomics Resources

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Protein Alignment SLC5A10 and CG31262

DIOPT Version :9

Sequence 1:XP_016879680.2 Gene:SLC5A10 / 125206 HGNCID:23155 Length:649 Species:Homo sapiens
Sequence 2:NP_001138069.2 Gene:CG31262 / 318649 FlyBaseID:FBgn0051262 Length:579 Species:Drosophila melanogaster


Alignment Length:701 Identity:142/701 - (20%)
Similarity:240/701 - (34%) Gaps:227/701 - (32%)


- Green bases have known domain annotations that are detailed below.


Human    15 QLSVADIIVITVYFALNVAVGIW------------SSCRASRNT------VNGYFLAGRDMTWWP 61
            :....|.:|:.....|:...||:            |....:|.|      ::.|.:..|:|...|
  Fly     5 RFGTVDYLVLVAMTLLSTGTGIYFGALKKKHKNKKSVSEDNRRTNFGSEKIDEYLMGSRNMKVIP 69

Human    62 IGASLFASSEGSGLFIGLAGSGAAGGLAVAGFEWNATYVL---------LALAWVFVPIYISSEI 117
            :..:|:..:.    .||....         .:.:...|.|         :|.::|::|:|.:.:|
  Fly    70 VSITLYRVTS----IIGTPSE---------IYHYGTQYYLIIVAIILQGIAFSYVYLPVYSALQI 121

Human   118 VTLPEYIQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITAL 182
            .:..||:..|: ...||...|.: .:..:.|.:...:|..||.:....|.|.:|..::.:.....
  Fly   122 GSAYEYLGLRF-NSIIRTTASFM-YVFGILTYLPFIVYVPALSLSQVSGLNTHLIGLVIILACVT 184

Human   183 YTIAGGLAAVIYTDALQTLIMVVGAVILT----------IKAFDQIGGYGQLEAAYAQAIPSRTI 237
            ||..|||.||::||..|..:|.:..|.:.          :..||.....|:|           .:
  Fly   185 YTFMGGLKAVVHTDVWQVAVMFLSLVAVAFLAIYYSNGLVAVFDDAEQGGRL-----------ML 238

Human   238 ANTTCHLPRTDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCT----DQVIVQRSLSARDLNHAK 298
            |||.            ..|:.....|:.:..|.:     :|.:    .|.:|||.:|...|..::
  Fly   239 ANTN------------PSPYVRHTVWSVLIGGFS-----FWTSVNAGGQHMVQRYMSLPSLKKSR 286

Human   299 AGSILASYLKMLPMGLIIMPGMISRALFPGAHVYE-----ERHQVSVSRTDDVGCVVPSECLRAC 358
            ..|.:      ..:|:.|   .|:...|.|..::.     :.....:...||             
  Fly   287 QASFI------FTIGVSI---FIALCCFMGLLLFSKYKDCDPRSAGMILNDD------------- 329

Human   359 GAEVGCSNIAYPKLVMELMPI----------GLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIW 413
                            :|:|:          |:.||.||.:..|.:|||:|.||:.|.:|..||.
  Fly   330 ----------------QLLPLFVVQSVGHIYGMPGLFIAGIFGAGLSSLSSCFNTVSMVFLEDIV 378

Human   414 R---RLRPRSGERELLLVGRTGIPSTPPAPQSRLSFLLPETPPLERYLLGLVVMDLWLVIVALIG 475
            |   ::.|  .||:..::.:|.|     ..|..|:||:..   |.::|.|:              
  Fly   379 RGFFKMEP--SERQSTILIKTCI-----IFQGILAFLIVF---LLQHLRGI-------------- 419

Human   476 VSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWG-----LIAG--- 532
            :||.                 .|::|..|.....||.||:.:..||..|...|     |:||   
  Fly   420 LSVC-----------------NSISSITAGTSFGVFTLGMLFPWANTIGTAVGGLSSVLLAGWIS 467

Human   533 ----------------LVVGATRLVLEFLNPAPPCGEPD-TRPAVLGSIHYLH-FAVALFALSGA 579
                            |.|.....|.....|..|..:.| ..|....|.|::. ..|....:.||
  Fly   468 FGSQIAAASGQLKSGMLPVSVKECVGNVTLPEDPWVDQDQVFPLYRLSYHWVSPIGVVTAVVVGA 532

Human   580 VVVAGSLLTPPPQSVQIENLTWWTLAQDVPLGTKAGDGQTPQKHAFWARVC 630
            :|   ||:|.|                 ..:.|...:..:|..|.|..|.|
  Fly   533 LV---SLITKP-----------------ADIKTLHAELISPVIHRFLPREC 563

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SLC5A10XP_016879680.2 SLC5-6-like_sbd 17..649 CDD:320982 142/699 (20%)
CG31262NP_001138069.2 SLC5sbd_NIS-SMVT 9..522 CDD:271383 128/634 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165146457
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0591
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D243316at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.750

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