Protein Alignment Cd63 and Tsp39D

DIOPT Version :10

• Sequence 1: NP_031679.1
• Gene: Cd63 / 12512
• MGIID: 99529
• Length: 238
• Species: Mus musculus
• Sequence 2: NP_523612.3
• Gene: Tsp39D / 35405
• FlyBaseID: FBgn0032943
• Length: 235
• Species: Drosophila melanogaster
• Alignment Length: 242
• Identity: 78/242 - (32%)
• Similarity: 129/242 - (53%)
• Gaps: 22/242 - (9%)

Mouse     5 GGMKCVKFLLYVLLLAFCACAVGLIAIGVAVQVVLKQ----AITHETTAGSLLPVVIIAVGAFLF 65
            ||:.|||:|.:...|.|....:.:..:|..||:....    ...|..||    |::::.|||.:.
  Fly     4 GGLTCVKYLTFFCNLLFALTGLLIFLVGGMVQLNYAHYSNFVSDHVWTA----PIILMIVGAAVA 64

Mouse    66 LVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAVAIAGYVFRDQVKSEFNKSFQQQMQNYLK-- 128
            ::.|:|||||.||:.|::::||:...:|.|.|:.:.:||||....:.......|...||:|.:
  Fly    65 VICFLGCCGALKESSCMILSFALLAVVIFLFEIGLGLAGYVKHTGLHQIMESQFNSTMQHYKERA 129

Mouse   129 DNKTATILDKLQKENNCCGASNYTDWENIPGMAKDRVPDSCC--INITVG--CGNDFKESTIHTQ 189
            |.:.|..|  ||.|.:|||.:...|||.:  .....:|.:||  ||::..  |.|  ..:|.|
  Fly   130 DYRDAWTL--LQTELDCCGINGPNDWETV--YRNSTLPAACCSVINLSEAKECTN--THATQH-- 186

Mouse   190 GCVETIAIWLRKNILLVAAAALGIAFVEVLGIIFSCCLVKSIRSGYE 236
            ||::.:...|....|::|:..||:|.:::|.|:|:|||.:|.|..|:
  Fly   187 GCLQKLLEILDSKTLILASVVLGVAGIQMLTILFACCLYRSFRRSYD 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cd63	NP_031679.1	Tetraspanin	10..229	CDD:459767	72/228 (32%)
		CD63_LEL	105..203	CDD:239419	30/103 (29%)
		Lysosomal targeting motif. /evidence=ECO:0000269|PubMed:21041449	234..238		1/3 (33%)
Tsp39D	NP_523612.3	Tetraspanin	9..226	CDD:459767	72/228 (32%)
		tetraspanin_LEL	131..>167	CDD:351888	12/39 (31%)