Protein Alignment MSI2 and msi2b

DIOPT Version :10

• Sequence 1: XP_005257072.1
• Gene: MSI2 / 124540
• HGNCID: 18585
• Length: 346
• Species: Homo sapiens
• Sequence 2: NP_957403.1
• Gene: msi2b / 394084
• ZFINID: ZDB-GENE-040426-1268
• Length: 408
• Species: Danio rerio
• Alignment Length: 395
• Identity: 304/395 - (76%)
• Similarity: 313/395 - (79%)
• Gaps: 62/395 - (15%)

Human     1 MEANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFG 65
            ||.:|||.||||.||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish     1 MEGDGSQATSGSPNDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFG 65

Human    66 FVTFADPASVDKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYF 130
            ||||||.|||||||.||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish    66 FVTFADAASVDKVLAQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYF 130

Human   131 EQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPG 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   131 EQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPG 195

Human   196 TRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYGYQFPGFPAAAYGPV-AAAAVAA 259
            ||||||||||||||||||||||.|||.||||||||.||||||.||||||||.||||| |||||||
Zfish   196 TRGRARGLPYTMDAFMLGMGMLSYPNIVATYGRGYTGFAPSYSYQFPGFPATAYGPVAAAAAVAA 260

Human   260 ARGSVLNS-----YSAQ--------PNFGAPASPA------------------------------ 281
            ||||...:     |:|.        |::|..:||:
Zfish   261 ARGSGRGARGRGGYAAYPQSTGPGFPDYGFYSSPSDQRGPPFSFADYGSLGPQAAQLLQSEHATS 325

Human   282 ------------------GSNPARPGGFPGANSPGPVADLYGPASQDSGVGNYISAASPQPGSGF 328
                              |:||.|||.||||:|||||||||||.|||||||||||||||||||||
Zfish   326 ACNSPLQHLASPDQYKSPGTNPPRPGAFPGASSPGPVADLYGPTSQDSGVGNYISAASPQPGSGF 390

Human   329 GHGIA 333
            ||.||
Zfish   391 GHSIA 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MSI2	XP_005257072.1	RRM1_MSI2	17..109	CDD:410153	89/91 (98%)
		RRM2_MSI	111..184	CDD:240769	72/72 (100%)
msi2b	NP_957403.1	RRM1_MSI2	17..109	CDD:410153	89/91 (98%)
		RRM2_MSI	111..184	CDD:240769	72/72 (100%)