Protein Alignment MSI2 and msi2b

DIOPT Version :9

• Sequence 1: XP_005257071.1
• Gene: MSI2 / 124540
• HGNCID: 18585
• Length: 346
• Species: Homo sapiens
• Sequence 2: NP_957403.1
• Gene: msi2b / 394084
• ZFINID: ZDB-GENE-040426-1268
• Length: 408
• Species: Danio rerio
• Alignment Length: 408
• Identity: 317/408 - (77%)
• Similarity: 326/408 - (79%)
• Gaps: 62/408 - (15%)

Human     1 MEANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFG 65
            ||.:|||.||||.||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish     1 MEGDGSQATSGSPNDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFG 65

Human    66 FVTFADPASVDKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYF 130
            ||||||.|||||||.||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish    66 FVTFADAASVDKVLAQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYF 130

Human   131 EQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPG 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   131 EQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPG 195

Human   196 TRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYGYQFPGFPAAAYGPV-AAAAVAA 259
            ||||||||||||||||||||||.|||.||||||||.||||||.||||||||.||||| |||||||
Zfish   196 TRGRARGLPYTMDAFMLGMGMLSYPNIVATYGRGYTGFAPSYSYQFPGFPATAYGPVAAAAAVAA 260

Human   260 ARGSVLNS-----YSAQ--------PNFGAPASPA------------------------------ 281
            ||||...:     |:|.        |::|..:||:
Zfish   261 ARGSGRGARGRGGYAAYPQSTGPGFPDYGFYSSPSDQRGPPFSFADYGSLGPQAAQLLQSEHATS 325

Human   282 ------------------GSNPARPGGFPGANSPGPVADLYGPASQDSGVGNYISAASPQPGSGF 328
                              |:||.|||.||||:|||||||||||.|||||||||||||||||||||
Zfish   326 ACNSPLQHLASPDQYKSPGTNPPRPGAFPGASSPGPVADLYGPTSQDSGVGNYISAASPQPGSGF 390

Human   329 GHGIAGPLIATAFTNGYH 346
            ||.|||||||||||||||
Zfish   391 GHSIAGPLIATAFTNGYH 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MSI2	XP_005257071.1	RRM1_MSI2	17..109	CDD:410153	89/91 (98%)
		PABP-1234	<35..343	CDD:130689	282/369 (76%)
		RRM2_MSI	111..184	CDD:240769	72/72 (100%)
msi2b	NP_957403.1	RRM	<2..162	CDD:223796	153/159 (96%)
		RRM1_MSI	23..97	CDD:241020	71/73 (97%)
		RRM2_MSI	111..184	CDD:240769	72/72 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C194327919
Domainoid	1	1.000	276	1.000	Domainoid score	I8400
eggNOG	1	0.900	-	-		E1_KOG4205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H62199
Inparanoid	1	1.050	582	1.000	Inparanoid score	I5500
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG47546
OrthoDB	1	1.010	-	-		D1565323at2759
OrthoFinder	1	1.000	-	-		FOG0000417
OrthoInspector	1	1.000	-	-		otm27011
orthoMCL	1	0.900	-	-		OOG6_101082
Panther	1	1.100	-	-	LDO	PTHR48032
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1869
SonicParanoid	1	1.000	-	-		X310
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	1	1.500	-	-
	17	17.300