DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment OR4D2 and ser-1

DIOPT Version :9

Sequence 1:	NP_001004707.1	Gene:	OR4D2 / 124538	HGNCID:	8294	Length:	307	Species:	Homo sapiens
Sequence 2:	NP_001024728.1	Gene:	ser-1 / 181716	WormBaseID:	WBGene00004776	Length:	683	Species:	Caenorhabditis elegans

Alignment Length:	158	Identity:	43/158 - (27%)
Similarity:	76/158 - (48%)	Gaps:	14/158 - (8%)

- Green bases have known domain annotations that are detailed below.

Human    27 LFLMFLFVYITTVMGNILIIITVTSDSQLHTPMYFLLRNLAVLDLCFSSVTAP-KMLVDLLSEKK 90
            |||:.:...| .::||.|:.:.:.:|.:||....:.|.:||:.||....:..| .::|::.....
Worm    59 LFLLPVLCLI-GLIGNFLVCVAIATDRRLHNVTNYFLFSLALADLLVCCIVMPLSIVVEVRHGVW 122

Human    91 TISYQGCMGQIFFFHFLGGAMVFFLSVMAFDRLIAISRPLRYVTVMNTQLWVGLVVATWVGGFVH 155
            |.|...|:..::...||..|.:..:||::.||.:.||:|||......|.:::.:.: .||
Worm   123 TWSVSMCLLYVYSDVFLCSASIVHMSVISLDRYLGISQPLRTRNRSKTLIFIKIAI-VWV----- 181

Human   156 SIVQLALMLPLPFCG----PNILDNFYC 179
              |.|.:..|:....    .|||.|..|
Worm   182 --VTLLVSCPIAVLAMHDTANILRNNQC 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
OR4D2	NP_001004707.1	7tm_4	31..301	CDD:304433	40/154 (26%)
OR4D2	NP_001004707.1	7tm_1	41..287	CDD:278431	39/144 (27%)
ser-1	NP_001024728.1	7tmA_5-HT2	56..438	CDD:320180	43/158 (27%)
		TM helix 1	57..83	CDD:320180	7/24 (29%)
		TM helix 2	90..116	CDD:320180	6/25 (24%)
		TM helix 3	129..159	CDD:320180	8/29 (28%)
		TM helix 4	170..193	CDD:320180	6/30 (20%)
		TM helix 5	211..240	CDD:320180
		TM helix 6	365..395	CDD:320180
		TM helix 7	406..431	CDD:320180
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910