Protein Alignment METTL23 and CG5013

DIOPT Version :10

• Sequence 1: NP_001073979.3
• Gene: METTL23 / 124512
• HGNCID: 26988
• Length: 190
• Species: Homo sapiens
• Sequence 2: NP_650520.1
• Gene: CG5013 / 41951
• FlyBaseID: FBgn0038396
• Length: 247
• Species: Drosophila melanogaster
• Alignment Length: 189
• Identity: 89/189 - (47%)
• Similarity: 124/189 - (65%)
• Gaps: 10/189 - (5%)

Human     2 YVWPCAVVLAQYLWFHRRSLPGKAILEIGAGVSLPGILAAKCGAEVILSDSSELPHCLEVCRQSC 66
            |.||||.:||.:||..|::|.||.|||:|:|.:|||||||||.|:|:|:|:..||..|...|:||
  Fly    52 YTWPCAPILAHFLWERRQTLAGKRILELGSGTALPGILAAKCRAQVVLTDNCILPKSLAHIRKSC 116

Human    67 QMNNLP---HLQVVGLTWGHISWDLLALPPQDIILASDVFFEPEDFEDILATIYFLMHKNPKVQL 128
            ..|.|.   .:.||||:||.:...:..|||.|:|:|:|.|::|..||||:.|:.||:.:|...:.
  Fly   117 LANQLQPGVDIDVVGLSWGLLLNSVFRLPPLDLIIAADCFYDPSVFEDIVVTVAFLLERNAGAKF 181

Human   129 WSTYQVRSADWSLEALLYKWDMKCVHIPLESFDADKE---DIAESTLPGRHTVEMLVIS 184
            ..|||.||||||:||||.||.::.:.|.:|  |..||   |:.|  ..|.||:.:|.|:
  Fly   182 IFTYQERSADWSIEALLKKWKLQALPISME--DIGKESGVDLLE--FMGGHTIHLLEIT 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
METTL23	NP_001073979.3	AdoMet_MTases	3..126	CDD:473071	61/125 (49%)
CG5013	NP_650520.1	Nnt1	<54..>165	CDD:443104	55/110 (50%)