Protein Alignment Ccnd1 and CycD

DIOPT Version :10

• Sequence 1: NP_001366177.1
• Gene: Ccnd1 / 12443
• MGIID: 88313
• Length: 317
• Species: Mus musculus
• Sequence 2: NP_523355.2
• Gene: CycD / 32551
• FlyBaseID: FBgn0010315
• Length: 477
• Species: Drosophila melanogaster
• Alignment Length: 293
• Identity: 107/293 - (36%)
• Similarity: 162/293 - (55%)
• Gaps: 37/293 - (12%)

Mouse    11 ETIRRAYPDTNLLNDRVLRAMLKTEETCAPSVSYFKCVQKEIVPSMRKIVATWMLEVCEEQKCEE 75
            :.:..|..|..|.:||.|...||.||........:..:||:|.|.||||||.||:|||.|:.|:|
  Fly   136 DNVNTAIGDPTLYSDRCLENFLKVEEKHHKIPDTYFSIQKDITPPMRKIVAEWMMEVCAEENCQE 200

Mouse    76 EVFPLAMNYLDRFLSLEPLKKSRLQLLGATCMFVASKMKETI--PLTAEKLCIYTDNSIRPEELL 138
            ||..||:||:|||||.:.::|::||:|.|.|:.:|||::|..  .|:.:.|.:||||||..::|:
  Fly   201 EVVLLALNYMDRFLSSKSVRKTQLQILAAACLLLASKLREPSCRALSVDLLVVYTDNSIYKDDLI 265

Mouse   139 QMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEA-----DENKQTIRKHAQTFVALCATDVKFISN 198
            :.||.::::|.|:|:::||.||:|..:.::|..     |.|...:|.|||.|::|.|.:.||...
  Fly   266 KWELYVLSRLGWDLSSVTPLDFLELLMMRLPIGSKNFPDINIGKVRGHAQAFISLAAKEHKFAKF 330

Mouse   199 PPSMVAAGSVVAAMQGL--NLGSPNNFLSCYRTTHFLSRVIKCDPVKALATGLWLNKDPLHLRPP 261
            ..|.:||.|:.|:|.||  :|.|.:|.       |||               |.|..|   |...
  Fly   331 SASTIAASSIAASMNGLKWHLRSGHNL-------HFL---------------LSLMTD---LTSV 370

Mouse   262 LQDCLRACQEQIEALLESSLRQAQQ---NVDPK 291
            .|..:|.|...:|.:.:...|..:.   |:|||
  Fly   371 EQAQVRDCMLHMEDIFKEHSRNLEPFLVNIDPK 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ccnd1	NP_001366177.1	CYCLIN_CCND1_rpt1	3..151	CDD:410276	61/141 (43%)
		CYCLIN_CCND1_rpt2	156..287	CDD:410279	40/140 (29%)
CycD	NP_523355.2	CYCLIN_SF	144..278	CDD:477360	60/133 (45%)
		CYCLIN_CCND_rpt2	283..387	CDD:410220	39/128 (30%)