DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cbx2 and rhi

DIOPT Version :9

Sequence 1:	XP_006532166.1	Gene:	Cbx2 / 12416	MGIID:	88289	Length:	594	Species:	Mus musculus
Sequence 2:	NP_536794.1	Gene:	rhi / 44879	FlyBaseID:	FBgn0004400	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	308	Identity:	62/308 - (20%)
Similarity:	96/308 - (31%)	Gaps:	116/308 - (37%)

- Green bases have known domain annotations that are detailed below.

Mouse    74 SREHEKEVQ----------NRKRGKRPRGRPRKHTVTSSCSRRSKLKASTATGNREPCSCYPGAS 128
            :::|.|.||          |:|:||..:                    .|| |..:....||...
  Fly   112 TQQHSKSVQAKNTAGMSKMNQKKGKNIK--------------------KTA-GKIKDIENYPKTQ 155

Mouse   129 SGAASPSTSPFCALSSRIAAAALLDHAQLPLALETLHQGSQRAEPDAPSKSKSSSSSSSSTSSSS 193
                .||||.....|:.:     .|                 ..|.|.:.:...|....|..|..
  Fly   156 ----MPSTSQVSTDSTEV-----FD-----------------GNPSATTTNMIKSPRIQSLFSDL 194

Mouse   194 SSDEEEDDSDLDSKRGPRGRETHPVPQKKAQILVAKPELKD-PIRKKRG-----RKPLPPEQKAA 252
            :..|...|.|:    |....:|.|    |::.|:..|:.:| |:..|..     ||...|.|.:.
  Fly   195 NLIEPTKDKDV----GDTSLKTPP----KSRRLIEFPQREDAPLSSKHVSPMLIRKESQPLQSSC 251

Mouse   253 RRPVSLAKVLKTTRKDLGTSAAKLPPPLSAPVAGLAALKAHTKEACGGPSTMATPENLASLMKGM 317
                       |...|||.|::.:..|..:..:...::|.          |.:.|:.|..:.  .
  Fly   252 -----------TDDSDLGESSSSMSLPTVSSTSSEKSIKV----------TKSEPKTLGQIK--F 293

Mouse   318 AGSPSRGGIWQSSIVHYMNRMSQSQVQAASRLALKAQATNKCGLGLDL 365
            :...|.||                  .|||.|.    |..:..:||||
  Fly   294 SSRSSDGG------------------HAASSLG----APKEGDIGLDL 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
Cbx2	XP_006532166.1	CBX7_C	553..585	CDD:375056
rhi	NP_536794.1	CHROMO	22..72	CDD:237991
rhi	NP_536794.1	ChSh	357..411	CDD:294039
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010