DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cbx2 and CG8289

DIOPT Version :9

Sequence 1:	XP_006532166.1	Gene:	Cbx2 / 12416	MGIID:	88289	Length:	594	Species:	Mus musculus
Sequence 2:	NP_573229.1	Gene:	CG8289 / 32741	FlyBaseID:	FBgn0030854	Length:	336	Species:	Drosophila melanogaster

Alignment Length:	216	Identity:	54/216 - (25%)
Similarity:	78/216 - (36%)	Gaps:	36/216 - (16%)

- Green bases have known domain annotations that are detailed below.

Mouse    40 KLDRQWGSLGNG-GWRLKPEKGLQAGLLKADWRCVSREHEKEVQN--------RKRGKRPRGRPR 95
            ::|:| .|.|.| ..|..|.|      .||.....|...:.:.|.        ..|.||..|:.|
  Fly    25 EIDQQ-KSNGTGRSSRKTPNK------RKAKLTVASDSEDSDCQTSTSNVDVPAARNKRKVGKAR 82

Mouse    96 KHTVTSSCSRRSKLKASTATGNREPCSCYPGASSGAASPSTSPFCALSSRIAAAALLDHAQLPLA 160
            ..| ||......|:....:..:.......|.|.|....|:..   ..:.|.......|..:||
  Fly    83 NAT-TSPRKNGKKIVIEDSDDDANHSDVDPSADSSPRKPNIK---RQTRRSVRGETEDSNELP-- 141

Mouse   161 LETLHQGSQRAEPDAPS---KSKSSSSSSSSTSSSSSSDEEEDDSDLDSKRGPRGRETHPVPQKK 222
                  .:.:|...|.|   |.|.|.:|:||..:.....|::.:||:|:  |... |....|||.
  Fly   142 ------STSKASAHASSPIKKRKLSRASTSSVKNGKKVAEKDSESDVDA--GTED-EKSAQPQKV 197

Mouse   223 AQILVAKPELKDPIRKKRGRK 243
            |....:.|..|.  .|.|||:
  Fly   198 AAKSKSSPNAKK--AKGRGRR 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
Cbx2	XP_006532166.1	CBX7_C	553..585	CDD:375056
CG8289	NP_573229.1	CHROMO	233..284	CDD:214605
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920