Protein Alignment Serpinh1 and Spn88Eb

DIOPT Version :9

• Sequence 1: NP_001104513.1
• Gene: Serpinh1 / 12406
• MGIID: 88283
• Length: 417
• Species: Mus musculus
• Sequence 2: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Alignment Length: 452
• Identity: 95/452 - (21%)
• Similarity: 175/452 - (38%)
• Gaps: 73/452 - (16%)

Mouse     1 MRSLLLGTLCLLAVALAAEVKKPLEAAAPGTAEKLS--SKATTLAERSTGLAFSLYQAMAKDQAV 63
            |.:..|..|.||.|...|.:.||          :||  ::.:.:.:.....:.:|.:.:.:....
  Fly     1 MHTFSLVLLALLPVVTIAALDKP----------ELSFLNEFSQIFKGERDFSLALMKQIREIYPS 55

Mouse    64 ENILLSPLVVASSLGLVSLGGKATT------------ASQAKAVLSAEKL--RDEEVHTGLGELL 114
            .|:..||....::|.|........|            |...:.||.:..|  |.:|.......:.
  Fly    56 GNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNKQQVLVSYTLAQRQDEFRWRQSPME 120

Mouse   115 RSLSN----STARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFR-DKRSALQSINE 174
            .|.:|    ....||:.|..:.|||.:                    .:::|: |..:.|:.||:
  Fly   121 LSSANRIFVDRTINVSNKFNTLLYGAT--------------------KELDFKNDPETGLKEIND 165

Mouse   175 WASQTTDGKLPEVTKDVERTDGALLV--NAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVTMMH 237
            |.:..|..::.::....|.|...:||  ||.:.|..|..:|..:....:.|.:.......|.|||
  Fly   166 WIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMH 230

Mouse   238 RTGLYNYYDDEKEKLQMVEMPL--------AHKLS-------SLIILMPHHVE-PLERLEKLLTK 286
            :||.:....||..:.|::::|.        .|..:       |:||::|:..: .|.|:...|..
  Fly   231 KTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKISLNRVISRLNA 295

Mouse   287 EQLKAWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVF 351
            :.:|.|..:...:.:.:||||...|...:|...|:.:|:.....:|.......:....|.:....
  Fly   296 DSVKKWFERALPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTRNATFGDLTADPISLVIDDAQ 360

Mouse   352 HATAFEWDTEGNPFDQD---IYGREELR-SPKLFYADHPFIFLVRDNQSGSLLFIGRLVRPK 409
            |....:.|..|:.....   :..|...: .|..|..:|||:||:.|.:..::||.|....|:
  Fly   361 HLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDTILFAGVYSDPR 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Serpinh1	NP_001104513.1	serpinH1_CBP1	35..416	CDD:381003	86/418 (21%)
		Prevents secretion from ER. /evidence=ECO:0000305	414..417
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	83/400 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010