DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Serpina6 and Spn42Dd

DIOPT Version :9

Sequence 1:	NP_031644.1	Gene:	Serpina6 / 12401	MGIID:	88278	Length:	397	Species:	Mus musculus
Sequence 2:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster

Alignment Length:	403	Identity:	110/403 - (27%)
Similarity:	191/403 - (47%)	Gaps:	45/403 - (11%)

- Green bases have known domain annotations that are detailed below.

Mouse     6 YTCLFWLCTSGLWTTQAVTDEDSSSHRDLAPTNVDFAFNLYKRLVALNSDKNTLISPVSISMALA 70
            |.|:|      ||.|........               .:|:.|...::::|.::|||||...|:
  Fly     3 YLCIF------LWVTSVACQTSK---------------EIYQLLSKSHTNQNLVVSPVSIETILS 46

Mouse    71 MLSLSTRGST--QYLENLGFNMSKMSEAEIHQGFQYLNSLLQQSDTGLEMNMGNVMFLLQNLKLK 133
            |:.:...|||  :....||. .|:..||...:....||. ||..:.|..:.:.|.:::.....|.
  Fly    47 MVFMGAEGSTAKELQSALGL-PSEDKEAVAARYGALLND-LQGQEEGPILKLANRIYVNDQYSLN 109

Mouse   134 DSFLADTKHYYESEALTIPSKDWTKAGEQINNHVKNKTQGKIEHVV--SDLDSSATLILINYIFL 196
            .::....:..::|||.:|...:...|.|:||..|.::|.|||:.::  ..:.|....:|:|.|:.
  Fly   110 QNYNLAVREPFKSEAESISLTNGPVAAERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYF 174

Mouse   197 KGIWKLPFSPENTREEDFYVNETSTVKVPMMVQSGNI--SYFRDSAIPCQMVQMNYVGNGTTF-I 258
            ||.|:..|.|..||...|.|....:|.|.||.|.|..  :||||  :..|::::.|:.:..:. |
  Fly   175 KGQWESKFDPAKTRASTFQVTANKSVPVQMMAQMGTFRANYFRD--LDAQVIELPYLNSNLSMTI 237

Mouse   259 ILPDQGQMDTVVAALNRDTIDRWGKLMIPRQMNLYIPKFSMSDTYDLQDVLADVGIKDLFTNQSD 323
            .||.:.:   .::|| .:.|..:.:.::.:::.|.:|||.:....:|::.|..:||::|||::||
  Fly   238 FLPREVE---GLSAL-EEKIVGFARPLVAKEVYLKLPKFKIEFRDELKETLEKLGIRELFTDKSD 298

Mouse   324 ----FADTTKDTPLTLTVLHKAMLQL-DEGNVLPAATNGPPVHLPSESFTLKYNRPFIFLAFDKY 383
                |||  |.......|.|||.|:: :||.....||:....:....|..|..:.||.|:..|..
  Fly   299 LSGLFAD--KSGGKVSQVSHKAFLEVNEEGAEAAGATSVAVTNRAGFSTFLMADHPFAFVIRDAN 361

Mouse   384 TWSSLMMSQVMNP 396
            |  .....:|::|
  Fly   362 T--IYFQGRVVSP 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Serpina6	NP_031644.1	SERPIN	43..396	CDD:214513	103/364 (28%)
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	102/379 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020