Protein Alignment Runx3 and run

DIOPT Version :9

• Sequence 1: NP_062706.2
• Gene: Runx3 / 12399
• MGIID: 102672
• Length: 423
• Species: Mus musculus
• Sequence 2: NP_001285501.1
• Gene: run / 33059
• FlyBaseID: FBgn0003300
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 476
• Identity: 149/476 - (31%)
• Similarity: 209/476 - (43%)
• Gaps: 124/476 - (26%)

Mouse    38 GGGGGKMGENSGALSAQATAGPGGRTR-PEVRSMVDVLA-------DHAGELVRTDSPNFLCSVL 94
            |.....:..|:.:.|:.||..|....: |.  ||.|:.|       ::.|||.:|.||:.|||.|
  Fly    69 GSSTPDLSTNNTSSSSNATTSPQNSAKMPS--SMTDMFASLHEMLQEYHGELAQTGSPSILCSAL 131

Mouse    95 PSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRS 159
            |:|||.||:||.||||:||.||||||:|::..||||||..||||.:..||||||:||||||||||
  Fly   132 PNHWRSNKSLPGAFKVIALDDVPDGTLVSIKCGNDENYCGELRNCTTTMKNQVAKFNDLRFVGRS 196

Mouse   160 GRGKSFTLTITVFTNPTQVATYHRAIKVTVDGPREPRRHRQ-------------------KIEDQ 205
            |||||||||||:.|.|.|:|:|.:|||||||||||||..:.                   .....
  Fly   197 GRGKSFTLTITIATYPVQIASYSKAIKVTVDGPREPRSKQSYGYPHPGAFNPFMLNPAWLDAAYM 261

Mouse   206 TKAFPDRFGD--------------LRMRVTPSTPSPRGSLSTTSHFSSQAQTPIQ---------- 246
            |..:.|.|..              .:...:..:|:|..|::|:   ||.|..|.:
  Fly   262 TYGYADYFRHQAAAQAAQVHHPALAKSSASSVSPNPNPSVATS---SSSAVQPSEYPHPAAAVAA 323

Mouse   247 -------------GSSDLNPFSDPRQFDRSFPTLQSLTESRFPDPRMHYPGAMSAAFPYSATPSG 298
                         |::...|::.|                :||...:....|..||.|::..|..
  Fly   324 AAGQPAAMMPSPPGAAPATPYAIP----------------QFPFNHVAAAAAAKAATPHAFHPYN 372

Mouse   299 TSLGSLSVAGMPA-SSRFHHTYLPPPYPGAPQSQSGPFQANPAPYHLFY----GASSGSYQFSMA 358
            .:    :.||:.| ::..||.  ..|...:|.| |.|..::|...|:..    ...:.|.....|
  Fly   373 FA----AAAGLRARNAALHHQ--SEPVHVSPAS-SRPSSSSPTQQHVLLKLNTSIETSSIHEQSA 430

Mouse   359 AAGGGER------------------SPTRMLTSCPSGASVSAGNLMNPSLGQADGVEADGSHSNS 405
            :.|..:.                  :|.||  .|    .:.|.:.|.|...::.......|...|
  Fly   431 SDGDSDDEQIDVVKSEFDLDKSLDVAPLRM--RC----DLKAPSAMKPLYHESGPGAVANSRQPS 489

Mouse   406 P---TALSTPGRMDEAVWRPY 423
            |   |.:.:.....:.|||||
  Fly   490 PETTTKIKSAAVQQKTVWRPY 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Runx3	NP_062706.2	Runt	77..198	CDD:279225	86/120 (72%)
		RunxI	328..423	CDD:285676	23/119 (19%)
run	NP_001285501.1	Runt	114..235	CDD:279225	86/120 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832159
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3982
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000993
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11950
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X738
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.890