Protein Alignment Runx3 and lz

DIOPT Version :9

• Sequence 1: NP_062706.2
• Gene: Runx3 / 12399
• MGIID: 102672
• Length: 423
• Species: Mus musculus
• Sequence 2: NP_511099.2
• Gene: lz / 31883
• FlyBaseID: FBgn0002576
• Length: 826
• Species: Drosophila melanogaster
• Alignment Length: 544
• Identity: 164/544 - (30%)
• Similarity: 212/544 - (38%)
• Gaps: 201/544 - (36%)

Mouse    13 YTPTFIRDPSTS-------------RRFTPPSTAFPCGGGGGG---------------------- 42
            :.|..:...|||             :..|..:||  .|||.||
  Fly   151 HPPAMVTSSSTSPTGNGWSSSTGDFKGITAVATA--TGGGVGGATQGATASTGATAAEVLAVSSS 213

Mouse    43 -KMGENS---GALSAQATAGPGGRTRPEVRSMV---------------------DVL-------- 74
             .:|.:|   ||.:..|.:|..|.|.....|..                     |:|
  Fly   214 ASVGSSSPTGGASNGTAHSGHSGHTGGHSSSTASNNNNNGASNSNSNNNNAVHQDLLWMERLVQK 278

Mouse    75 --ADHAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENYSAELR 137
              .:|.||||||.:|.||||.||:|||.|||||:|||||||.:|.|||.||:.||||||..||||
  Fly   279 RQQEHPGELVRTSNPYFLCSALPAHWRSNKTLPMAFKVVALAEVGDGTYVTIRAGNDENCCAELR 343

Mouse   138 NASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPTQVATYHRAIKVTVDGPREPRR----- 197
            |.:..|||.||:||||||||||||||||||||||.|:|.|||||.:|||||||||||||.
  Fly   344 NFTTQMKNDVAKFNDLRFVGRSGRGKSFTLTITVATSPPQVATYAKAIKVTVDGPREPRSKTSPT 408

Mouse   198 ---HRQKIEDQTKAFPDRFGDLR--------------MRVTPSTPSPRGSLSTTSHFSSQAQ--- 242
               |.:.:....:.:.|.|...:              ..||.:..:...:.|..:..::.|.
  Fly   409 GGPHYRALGLGQRPYIDGFPSTKALHELESLRRSAKVAAVTTAAAAAATAASAANAVAAAAAAVA 473

Mouse   243 -TPIQGSSDL------------------NPFSDPRQFDRSFPTLQSLTESRFPDPRMHYPGAMSA 288
             ||..|...:                  :.:|.|..      |:.|       |.:::.|.|
  Fly   474 VTPTGGGGGVAAGGVAGGAGAGLVQQLSSNYSSPNS------TINS-------DCQVYKPNA--- 522

Mouse   289 AFPY--SATPSGT---SLGSLSVAGMPASSRFHHTY-------------LPPPYP---GAPQS-- 330
              |:  :|...|.   :.||.|.|.....|..||.:             ||||.|   .||.|
  Fly   523 --PHIQAAEMMGAGEWTNGSSSSAAAYYHSHAHHPHAHHAHAHLQHQMALPPPPPPPAAAPVSVG 585

Mouse   331 ---------------------------------QSGPFQAN-PAPYHLFYGASSGSYQFSMAAAG 361
                                             ::|.:.|: ||.....:|....:..:..|..|
  Fly   586 VGGNGATMGMGMGVGVGMGMNHYGGGYDSANSLEAGQYAAHLPAVLPEMHGHGFATDPYQTAGYG 650

Mouse   362 GGERSPTRMLTSCPSGASVSAGNL 385
            ||.          ..|.|.|...|
  Fly   651 GGN----------TGGGSASKSEL 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Runx3	NP_062706.2	Runt	77..198	CDD:279225	93/128 (73%)
		RunxI	328..423	CDD:285676	15/94 (16%)
lz	NP_511099.2	Runt	283..404	CDD:279225	93/120 (78%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3982
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000993
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X738
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.870