Protein Alignment Runx1 and lz

DIOPT Version :9

• Sequence 1: NP_001104491.1
• Gene: Runx1 / 12394
• MGIID: 99852
• Length: 465
• Species: Mus musculus
• Sequence 2: NP_511099.2
• Gene: lz / 31883
• FlyBaseID: FBgn0002576
• Length: 826
• Species: Drosophila melanogaster
• Alignment Length: 440
• Identity: 158/440 - (35%)
• Similarity: 202/440 - (45%)
• Gaps: 110/440 - (25%)

Mouse    71 DHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNAT 135
            :||||||||.:|.||||.||.|||.|||||:|||||||.:|.|||.||:.||||||..|||||.|
  Fly   282 EHPGELVRTSNPYFLCSALPAHWRSNKTLPMAFKVVALAEVGDGTYVTIRAGNDENCCAELRNFT 346

Mouse   136 AAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRR-------- 192
            ..|||.||:||||||||||||||||||||||.|:|||||||.:|||:|||||||||.
  Fly   347 TQMKNDVAKFNDLRFVGRSGRGKSFTLTITVATSPPQVATYAKAIKVTVDGPREPRSKTSPTGGP 411

Mouse   193 HRQKLDDQTKPGSLSF--SERLSELEQLRR-------TAMRVSPHHPAPTPNPRASLNHSTAFNP 248
            |.:.|....:|....|  ::.|.|||.|||       |....:....|...|..|:...:.|..|
  Fly   412 HYRALGLGQRPYIDGFPSTKALHELESLRRSAKVAAVTTAAAAAATAASAANAVAAAAAAVAVTP 476

Mouse   249 -----------------------------QPQSQM-QDARQIQPSPP------------WSYDQS 271
                                         .|.|.: .|.:..:|:.|            |:...|
  Fly   477 TGGGGGVAAGGVAGGAGAGLVQQLSSNYSSPNSTINSDCQVYKPNAPHIQAAEMMGAGEWTNGSS 541

Mouse   272 YQYLGSITSSSVHP-----------------------ATPISPGRASGMTSLSAELSSRLSTAPD 313
            ........|.:.||                       |.|:|.|  .|....:..:...:.....
  Fly   542 SSAAAYYHSHAHHPHAHHAHAHLQHQMALPPPPPPPAAAPVSVG--VGGNGATMGMGMGVGVGMG 604

Mouse   314 LTAFG---------DPRQFPT-LPSISDPRMHYPGAFTYSPPVTSGIGIGMSAMSSASRYHTYLP 368
            :..:|         :..|:.. ||::. |.||..| |...|..|:|.|.|.:...|||:...
  Fly   605 MNHYGGGYDSANSLEAGQYAAHLPAVL-PEMHGHG-FATDPYQTAGYGGGNTGGGSASKSEL--- 664

Mouse   369 PPYPGS-SQAQAGPFQTGSPSYHLYYGASAGSYQFSMVGGERSPPRILPP 417
             .|.|| :||.:..:|      :..||:...:.|:   |.:.:||...||
  Fly   665 -DYGGSYNQAWSNGYQ------NYQYGSCLATAQY---GPQAAPPPQPPP 704

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Runx1	NP_001104491.1	Runt	72..193	CDD:307137	95/128 (74%)
		RunxI	375..465	CDD:312115	11/43 (26%)
lz	NP_511099.2	Runt	283..404	CDD:279225	95/120 (79%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836814
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3982
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000993
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X738
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.800