Protein Alignment Casp8 and Dcp-1

DIOPT Version :9

• Sequence 1: NP_001264855.1
• Gene: Casp8 / 12370
• MGIID: 1261423
• Length: 500
• Species: Mus musculus
• Sequence 2: NP_476974.1
• Gene: Dcp-1 / 37729
• FlyBaseID: FBgn0010501
• Length: 323
• Species: Drosophila melanogaster
• Alignment Length: 264
• Identity: 101/264 - (38%)
• Similarity: 136/264 - (51%)
• Gaps: 34/264 - (12%)

Mouse   248 YQMKNKPRGYCLIINNHDFSKAREDITQLRKMKDRKGTDCDKEALSKTFKELHFEIVSYDDCTAN 312
            |.|.:|.||..||. ||:|.    ||..|   |.|.||:.|.:.|.|.|:.|.|.:..:.||...
  Fly    71 YNMSHKHRGVALIF-NHEFF----DIPSL---KSRTGTNVDAQELKKAFENLGFAVSVHKDCKLR 127

Mouse   313 EIHEILEGYQSADHKNKDCFICCILSHGDKGVVYGTDGKEASIYDLTSYFTGSKCPSLSGKPKIF 377
            :|.:.:......||.:.||....|||||:.|.:|..| .:..:.::..|||.:.||||:||||:|
  Fly   128 DILKHVGKAAELDHTDNDCLAVAILSHGEHGYLYAKD-TQYKLDNIWHYFTATFCPSLAGKPKLF 191

Mouse   378 FIQACQGSNFQKGVPDEAGFEQQNHTLEVDSSSHKNY-IPDEADFLLGMATVKNCVSYRDPVNGT 441
            |||||||.....|:..|.|      ..|.|..|..:| ||..||||...:|:....|:|:..||:
  Fly   192 FIQACQGDRLDGGITLEKG------VTETDGESSTSYKIPIHADFLFSYSTIPGYFSWRNINNGS 250

Mouse   442 WYIQSLCQSLRERCPQGD--DILSILTGVNYDV-----SNKD-----DRRNKGKQMPQPTFTLRK 494
            ||:|||   :||....|.  |:|::||.||..|     ||..     ||:   ||:|..|..|.:
  Fly   251 WYMQSL---IRELNANGKKYDLLTLLTFVNQRVALDFESNVPATPMMDRQ---KQIPCLTSMLTR 309

Mouse   495 KLFF 498
            .|.|
  Fly   310 ILRF 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Casp8	NP_001264855.1	DED_Caspase_8_r1	23..104	CDD:260041
		DD	118..199	CDD:387368
		CASc	247..499	CDD:237997	101/264 (38%)
Dcp-1	NP_476974.1	CASc	71..313	CDD:214521	100/262 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810