Protein Alignment Casp2 and Strica

DIOPT Version :9

• Sequence 1: NP_031636.1
• Gene: Casp2 / 12366
• MGIID: 97295
• Length: 452
• Species: Mus musculus
• Sequence 2: NP_001260718.1
• Gene: Strica / 35528
• FlyBaseID: FBgn0033051
• Length: 527
• Species: Drosophila melanogaster
• Alignment Length: 432
• Identity: 86/432 - (19%)
• Similarity: 155/432 - (35%)
• Gaps: 97/432 - (22%)

Mouse    65 IITLEMRELIQAKGGSFSQNVEL--LNLLPKRGPQAFDAFCEALRETRQGHL------------- 114
            ::..|...:.|..|.:.:|::|.  ::|...|....:.:|......:...::
  Fly   145 LVKTEQTTVTQKNGRTVTQHLETHRVDLKGSRPKATWASFASTANSSTSSYVSPYRQKPSMAITC 209

Mouse   115 --------EDLLLTTLSDIQHVLPPLSCDYDTSLPFSVCESCPPHKQLRLSTDATEH---SLDNG 168
                    :....|:.|....:..|.......|...|:.:|.|......||:.||..   ||.:.
  Fly   210 TSPNIKTPKTTSSTSSSSASSITSPPKPSSSVSSISSIFKSAPKQVDKPLSSTATPKPFISLGSS 274

Mouse   169 DGPPCLLVKPCTPEFYQAHYQLAYRLQSQPRGLA--------------LVLSNVHFTGEKDLEFR 219
            .|     .||......|:  |.|....|...|::              .:.::..|..:.  |||
  Fly   275 GG-----TKPKVTAVAQS--QDAQGTISTSLGISKSSLTKNKLKPARVYIFNHERFDNKN--EFR 330

Mouse   220 SGGDVDHTTLVTLFKLLGYNVHVLHDQTAQEMQEKLQNFAQLPAHRVTDSCVVALLSHG------ 278
            .|...|...|...|:.|...|.|:.|.|...: :|.....|........:.|:.:||||
  Fly   331 KGSAQDVKVLRATFEQLKCKVEVITDATLVTI-KKTVRMLQTKDFEDKSALVLVILSHGTRHDQI 394

Mouse   279 -VEGGIYGVDGKLLQLQEVFRLFDNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHTQSPG 342
             .:...|.:|..:     ||.:..|.   :|::|||:.|:|||:|| ...|....|......||
  Fly   395 AAKDDDYSLDDDV-----VFPILRNR---TLKDKPKLIFVQACKGD-CQLGGFMTDAAQPNGSP- 449

Mouse   343 CEESDAGKEELMKMRLPTRSDMICGYACLKGNAAMRNTKRGSWYIEALTQVFSERACDMHVADML 407
                    .|::|          | |:..:|..:.| |:.|:.:|:.|.:..:.......:..::
  Fly   450 --------NEILK----------C-YSTYEGFVSFR-TEDGTPFIQTLCEALNRSGKTSDIDTIM 494

Mouse   408 VKVNALIKEREGYAPGTEFHRCKEMSEYCSTLCQQLYLFPGY 449
            :.|..::|.:.         :.:::....|||..: |:|..|
  Fly   495 MNVRQVVKMQS---------KDRQIPSVTSTLTSK-YVFGDY 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Casp2	NP_031636.1	CARD_CASP2	32..118	CDD:260040	8/75 (11%)
		CASc	192..447	CDD:214521	57/275 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..349		4/21 (19%)
Strica	NP_001260718.1	CASc	311..523	CDD:294037	55/254 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810