Protein Alignment Casp1 and Dcp-1

DIOPT Version :10

• Sequence 1: NP_033937.2
• Gene: Casp1 / 12362
• MGIID: 96544
• Length: 402
• Species: Mus musculus
• Sequence 2: NP_476974.1
• Gene: Dcp-1 / 37729
• FlyBaseID: FBgn0010501
• Length: 323
• Species: Drosophila melanogaster
• Alignment Length: 313
• Identity: 86/313 - (27%)
• Similarity: 138/313 - (44%)
• Gaps: 45/313 - (14%)

Mouse    79 EDC----YLAGILELQSAPSAETFVATE--DSKGGHPSSSETKEEQNKEDGTFPGLTGTLKFCPL 137
            ::|    |..||.....:.:..:|:..:  |:||..|.|..              :.|.....||
  Fly     3 DECVTRNYGVGIRSPNGSENRGSFIMADNTDAKGCTPESLV--------------VGGATAASPL 53

Mouse   138 EKAQKLWKENPSEIYPI-MNTTTRTRLALIICNTEF---QHLSPRVGAQVDLREMKLLLEDLGYT 198
             .|.|.....|.|.|.. .|.:.:.|...:|.|.||   ..|..|.|..||.:|:|...|:||:.
  Fly    54 -PANKFVARMPVERYASEYNMSHKHRGVALIFNHEFFDIPSLKSRTGTNVDAQELKKAFENLGFA 117

Mouse   199 VKVKENLTALEMVKEVKEFAACPEHKTSDSTFLVFMSHGIQEGICGTTYSNEVSDILKVDTIFQM 263
            |.|.::....:::|.|.: ||..:|..:|...:..:|||..    |..|:.:..  .|:|.|:..
  Fly   118 VSVHKDCKLRDILKHVGK-AAELDHTDNDCLAVAILSHGEH----GYLYAKDTQ--YKLDNIWHY 175

Mouse   264 MNTLKCPSLKDKPKVIIIQACRGEK-QGVVLLKDSVRDSEEDFLTDAIFEDDGIKKAHIEKDFIA 327
            .....||||..|||:..||||:|:: .|.:.|:..|.:::.:..|.        .|..|..||:.
  Fly   176 FTATFCPSLAGKPKLFFIQACQGDRLDGGITLEKGVTETDGESSTS--------YKIPIHADFLF 232

Mouse   328 FCSSTPDNVSWRHPVRGSLFIESLIKHM----KEYAWSCDLEDIFRKVRFSFE 376
            ..|:.|...|||:...||.:::|||:.:    |:|.....|..:.::|...||
  Fly   233 SYSTIPGYFSWRNINNGSWYMQSLIRELNANGKKYDLLTLLTFVNQRVALDFE 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Casp1	NP_033937.2	CARD_CASP1-like	6..87	CDD:260036	3/11 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	98..125		6/28 (21%)
		CASc	152..400	CDD:214521	69/234 (29%)
Dcp-1	NP_476974.1	CASc	71..313	CDD:214521	68/230 (30%)