DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Camk2g and lok

DIOPT Version :9

Sequence 1:	XP_006518551.1	Gene:	Camk2g / 12325	MGIID:	88259	Length:	588	Species:	Mus musculus
Sequence 2:	NP_477219.1	Gene:	lok / 35288	FlyBaseID:	FBgn0019686	Length:	476	Species:	Drosophila melanogaster

Alignment Length:	269	Identity:	98/269 - (36%)
Similarity:	153/269 - (56%)	Gaps:	11/269 - (4%)

- Green bases have known domain annotations that are detailed below.

Mouse    14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLS-AR------DHQKLEREARICRLLKHP 71
            |.:..:||.||:.:||......:.|::|.||:....|| ||      |..::..||:|.:.|.||
  Fly   174 YYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMKNLSHP 238

Mouse    72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRD 136
            .:||:||.:.:....|:|.:.:.||:|...|::.:..||..:....:|:..:|.::|...|.|||
  Fly   239 CVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKYLHDRGITHRD 303

Mouse   137 LKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVL---RKDPYGKPVDIW 198
            |||:|:||.:..:...:|::||||:..|| :........|||.|::||||   .::.|.|.||||
  Fly   304 LKPDNVLLETNDEETLLKVSDFGLSKFVQ-KDSVMRTLCGTPLYVAPEVLITGGREAYTKKVDIW 367

Mouse   199 ACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITA 263
            :.||:|:..|.|..||.||......||||.|.:.:..|.|.:|:..||.||||||.::|.:|.:.
  Fly   368 SLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKSVSQRAKLLINQMLIVDPERRPSI 432

Mouse   264 DQALKHPWV 272
            |..|:..|:
  Fly   433 DDVLQSSWL 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Camk2g	XP_006518551.1	STKc_CaMKII	12..303	CDD:270988	98/269 (36%)
Camk2g	XP_006518551.1	CaMKII_AD	456..583	CDD:285524
lok	NP_477219.1	FHA	39..156	CDD:238017
		STKc_Chk2	167..441	CDD:270986	97/267 (36%)
		S_TKc	174..441	CDD:214567	97/267 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910