Protein Alignment Pdia4 and CaBP1

DIOPT Version :10

• Sequence 1: NP_001355685.1
• Gene: Pdia4 / 12304
• MGIID: 104864
• Length: 699
• Species: Mus musculus
• Sequence 2: NP_609792.1
• Gene: CaBP1 / 34976
• FlyBaseID: FBgn0025678
• Length: 433
• Species: Drosophila melanogaster
• Alignment Length: 470
• Identity: 129/470 - (27%)
• Similarity: 190/470 - (40%)
• Gaps: 139/470 - (29%)

Mouse    58 NGVWVLNDGNFDNFVADKDTV-LLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIAVAKIDATSA 121
            :||..|...|||..|...|.: ::||||||||||:...|||:|:|..||.   .:.|..::|.:.
  Fly    25 DGVVELTPSNFDREVLKDDAIWVVEFYAPWCGHCQSLVPEYKKLAKALKG---VVKVGSVNADAD 86

Mouse   122 SMLASKFDVSGYPTIKIL--KKGQAVDYDGSRTQE--------EIVAKVREV--------SQPDW 168
            |.|:.:|.|.|:|||||.  .|....||:|.||.:        |:..||:.|        |....
  Fly    87 STLSGQFGVRGFPTIKIFGANKKSPTDYNGQRTAKAIAEAALAEVKKKVQGVLGGGGGSSSGGSG 151

Mouse   169 TPPPEVTLSLTKDNFDD-VVNNADIILVEFYAPWTVALLLFSLSFYQFAVLLSTHTGLLDVNAND 232
            :...:..:.||:||||. |:|:.||.||||:||
  Fly   152 SSSGDDVIELTEDNFDKLVLNSDDIWLVEFFAP-------------------------------- 184

Mouse   233 KSLMFQQFSVPVGPVLSFSPRRHSKIWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATEQTDL 297
                                      ||||||.||||:.||||||..:   :.|..:|||.....
  Fly   185 --------------------------WCGHCKNLAPEWAKAAKELKGK---VKLGALDATAHQSK 220

Mouse   298 AKRFDVSGYPTLKIFRKG--RPFD---YNGPREKYGIVDYMIEQ--SGPPSKEILTL--KQVQEF 353
            |..::|.||||:|.|..|  |..|   |:|.|....||.:..::  :..|:.|::.:  :...|.
  Fly   221 AAEYNVRGYPTIKFFPAGSKRASDAQEYDGGRTASDIVSWASDKHVANVPAPELIEIINESTFET 285

Mouse   354 LKDGDDVVIIGLFQGDGDPAYLQYQDAANNLREDYKFHHTFSPEIAKFLKVSLG--------KLV 410
            ..:|..:.::.:.     |..|.......|     ||..|......||.:...|        :|.
  Fly   286 ACEGKPLCVVSVL-----PHILDCDAKCRN-----KFLDTLRTLGEKFKQKQWGWAWAEGGQQLA 340

Mouse   411 LTHPEKFQSKYEPRFHVMD--------VQGSTEASAIKDYVVK------HALPLVGHRKTSNDAK 461
            |....:......|...|::        ::||.....|.:::..      |..|:.|
  Fly   341 LEESLEVGGFGYPAMAVVNFKKMKFSVLKGSFSKDGINEFLRDISYGRGHTAPVRG--------- 396

Mouse   462 RYSKRPLVVVYYSVD 476
              :|:|.:|   |||
  Fly   397 --AKKPAIV---SVD 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdia4	NP_001355685.1	pdi_dom	63..164	CDD:273454	45/119 (38%)
		ER_PDI_fam	173..691	CDD:273457	81/336 (24%)
CaBP1	NP_609792.1	PDI_a_P5	26..119	CDD:239299	41/95 (43%)
		PDI_a_P5	157..262	CDD:239299	52/165 (32%)
		P5_C	271..400	CDD:239281	23/149 (15%)