Protein Alignment SOCS4 and socs4

DIOPT Version :10

• Sequence 1: NP_543143.1
• Gene: SOCS4 / 122809
• HGNCID: 19392
• Length: 440
• Species: Homo sapiens
• Sequence 2: XP_021322920.1
• Gene: socs4 / 797891
• ZFINID: ZDB-GENE-070720-4
• Length: 423
• Species: Danio rerio
• Alignment Length: 448
• Identity: 202/448 - (45%)
• Similarity: 251/448 - (56%)
• Gaps: 103/448 - (22%)

Human     5 NENISKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESYSDAETVNGI-EKTEVSL----RN 64
            :|..:||.|.|||..||.||   |.|:.|.||.|...:.|:....|..:|. |:|..|.    |.
Zfish    45 SERKTKNSDTRPKNLRSWSA---DSYIRSIKKRSRGSRHETAPRGEEGDGADEQTARSASCPRRR 106

Human    65 QERKHSCS-SIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPIKN--CSSRHSSG--------LPS 118
            :||..||: ..|.|.|..|......|||:||.|||||||.|::|  ....|.||        |.|
Zfish   107 RERMCSCTIPGETDSDSPCRKALSRRSLRQKFQDAVGQCLPLRNHHHHHHHPSGSSRPFSVLLWS 171

Human   119 KRKIHISELMLDKCPFPPRSDLAFRWHFIKRHTAPINSKSDEWVSTDLSQTELRDGQLKRRNMEE 183
            |||||:||||.|||||.|:|:||..||.||:|
Zfish   172 KRKIHVSELMEDKCPFSPKSELAQCWHLIKKH--------------------------------- 203

Human   184 NINCFSHTNVQPCV-ITTDNALCREGPMTGSV-MNLVSNNSIEDSDMDSDDEILTLCTSSRKRNK 246
                  .||.:|.: |.|:    .:||:..|. ..|:|...|..:...|.|:
Zfish   204 ------GTNTKPSLSIETE----PKGPLLSSTPPTLLSWEQIGSTGASSLDD------------- 245

Human   247 PKWDLDDEILQLETPPKY---------HTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALLEG 302
              ||           |.:         ||  ||:  ||||||||||:||||||:|::.||.||||
Zfish   246 --WD-----------PSFALGDSQCCAHT--DYI--LVPDLLQINNSPCYWGVLDRFEAEQLLEG 293

Human   303 KPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGLLEHYKDP 367
            :||||||||||||::||||||||||||||||||||....||||..|||::....:||||:||.||
Zfish   294 QPEGTFLLRDSAQDEYLFSVSFRRYSRSLHARIEQNGKRFSFDGRDPCMYRDSSVTGLLKHYSDP 358

Human   368 SACMFFEPLLSTPLIRTFPFSLQHICRTVICNCTTYDGIDALPIPSSMKLYLKEYHYK 425
            |.|:|||||||.||.|.|||||||:||.|||:||||.||:|||:|.:::.:|::|||:
Zfish   359 STCLFFEPLLSRPLPRNFPFSLQHLCRAVICSCTTYQGIEALPLPYTLRHFLRQYHYR 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SOCS4	NP_543143.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29		11/23 (48%)
		SOCS	58..111	CDD:432667	25/59 (42%)
		SH2_SOCS4	275..375	CDD:198248	73/99 (74%)
		SOCS_SOCS4	384..439	CDD:239707	26/42 (62%)
socs4	XP_021322920.1	SOCS	100..150	CDD:432667	22/49 (45%)
		SH2	266..366	CDD:472789	73/99 (74%)
		SOCS	376..>416	CDD:470605	25/39 (64%)