Protein Alignment SOCS4 and Socs4

DIOPT Version :10

• Sequence 1: NP_543143.1
• Gene: SOCS4 / 122809
• HGNCID: 19392
• Length: 440
• Species: Homo sapiens
• Sequence 2: NP_543119.2
• Gene: Socs4 / 67296
• MGIID: 1914546
• Length: 436
• Species: Mus musculus
• Alignment Length: 439
• Identity: 381/439 - (86%)
• Similarity: 409/439 - (93%)
• Gaps: 3/439 - (0%)

Human     1 MAENNENISKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESYSDAETVNGIEKTEVSLRNQ 65
            |||||   |||||||||||||||||||||||||||||||||||||.|::|.:..:|..|:.||:|
Mouse     1 MAENN---SKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESCSESEAIGTVENVEIPLRSQ 62

Human    66 ERKHSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPIKNCSSRHSSGLPSKRKIHISELMLD 130
            ||:.||||||||||||||||||||||||||||||||||||||||.|||.||||||||||||||||
Mouse    63 ERQLSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPIKNCSGRHSPGLPSKRKIHISELMLD 127

Human   131 KCPFPPRSDLAFRWHFIKRHTAPINSKSDEWVSTDLSQTELRDGQLKRRNMEENINCFSHTNVQP 195
            |||||||||||||||||||||.|::..||||||.|||:.:|||.||||||.|::|.||||||.||
Mouse   128 KCPFPPRSDLAFRWHFIKRHTVPMSPNSDEWVSADLSERKLRDAQLKRRNTEDDIPCFSHTNGQP 192

Human   196 CVITTDNALCREGPMTGSVMNLVSNNSIEDSDMDSDDEILTLCTSSRKRNKPKWDLDDEILQLET 260
            ||||.::|.|..|.:|||:||||:|||||||||||:|||:||||||||||||:|::::||||||.
Mouse   193 CVITANSASCTGGHITGSMMNLVTNNSIEDSDMDSEDEIITLCTSSRKRNKPRWEMEEEILQLEA 257

Human   261 PPKYHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYLFSVSFR 325
            |||:|||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||
Mouse   258 PPKFHTQIDYVHCLVPDLLQISNNPCYWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYLFSVSFR 322

Human   326 RYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGLLEHYKDPSACMFFEPLLSTPLIRTFPFSLQ 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   323 RYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGLLEHYKDPSACMFFEPLLSTPLIRTFPFSLQ 387

Human   391 HICRTVICNCTTYDGIDALPIPSSMKLYLKEYHYKSKVRVLRIDAPEQQ 439
            |||||||||||||||||||||||.|||||||||||||||:||||.||||
Mouse   388 HICRTVICNCTTYDGIDALPIPSPMKLYLKEYHYKSKVRLLRIDVPEQQ 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SOCS4	NP_543143.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29		24/27 (89%)
		SOCS	58..111	CDD:432667	46/52 (88%)
		SH2_SOCS4	275..375	CDD:198248	98/99 (99%)
		SOCS_SOCS4	384..439	CDD:239707	51/54 (94%)
Socs4	NP_543119.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25		23/26 (88%)
		SOCS	55..106	CDD:432667	44/50 (88%)
		SH2_SOCS4	272..372	CDD:198248	98/99 (99%)
		SOCS_SOCS4	381..436	CDD:239707	51/54 (94%)