Protein Alignment SOCS4 and socs4

DIOPT Version :10

• Sequence 1: NP_543143.1
• Gene: SOCS4 / 122809
• HGNCID: 19392
• Length: 440
• Species: Homo sapiens
• Sequence 2: XP_031746340.1
• Gene: socs4 / 549828
• XenbaseID: XB-GENE-481718
• Length: 467
• Species: Xenopus tropicalis
• Alignment Length: 441
• Identity: 319/441 - (72%)
• Similarity: 363/441 - (82%)
• Gaps: 12/441 - (2%)

Human     1 MAENNENISKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESYSDAETVNGIEKTEVSLRNQ 65
            ||||.|:....:|||||:|||||||||||||||||||:|..|:...||.:|:|.:|..:.:.::|
 Frog    32 MAENIEDKLGELDVRPKSSRSRSADRKDGYVWSGKKLTWLNKNGHSSDGDTINVVEDEDCATQSQ 96

Human    66 ERKHSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPIKNCSSRHSSGLPSKRKIHISELMLD 130
            ||||||||||||||.||||:.||||||||||||||||||||.||:||||.|.|||||||||||||
 Frog    97 ERKHSCSSIELDLDRSCGHKILGRSLKQKLQDAVGQCFPIKTCSNRHSSTLSSKRKIHISELMLD 161

Human   131 KCPFPPRSDLAFRWHFIKRHTAPINSKSDEWVSTDLSQTELRDGQLKRRNMEENINCFSHTNVQP 195
            ||||||:||||:|||.|||||||::....|||..|....:.::.|:|.:|.:...:|....:..|
 Frog   162 KCPFPPKSDLAYRWHLIKRHTAPVSQTKGEWVINDGLDLDGKEIQVKDKNSDGGEDCLLDGHATP 226

Human   196 CVITTDN--ALCREGPMTGSVMNLVSNNSIEDSDMDSDDEILTLCTSSRKRNKPKWDLDDEILQL 258
            |.:...|  :|..:|          |.:|.||||:|||||.:|||:||||||||||:.|||..|.
 Frog   227 CKVNIGNVESLGTKG----------SRSSKEDSDLDSDDEAVTLCSSSRKRNKPKWETDDESFQA 281

Human   259 ETPPKYHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYLFSVS 323
            ||||||||||||||||||||.|||||||||||||:||||||||||||||||||||||||||||||
 Frog   282 ETPPKYHTQIDYVHCLVPDLFQINNNPCYWGVMDRYAAEALLEGKPEGTFLLRDSAQEDYLFSVS 346

Human   324 FRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGLLEHYKDPSACMFFEPLLSTPLIRTFPFS 388
            ||||||||||||||||||||||||||||||:|::|||||||||||:|||||||||:||.|||||:
 Frog   347 FRRYSRSLHARIEQWNHNFSFDAHDPCVFHAPNVTGLLEHYKDPSSCMFFEPLLSSPLNRTFPFT 411

Human   389 LQHICRTVICNCTTYDGIDALPIPSSMKLYLKEYHYKSKVRVLRIDAPEQQ 439
            ||||||..||..|.||||||||:|||||||||||||||||||.|:|||||:
 Frog   412 LQHICRAAICTSTNYDGIDALPVPSSMKLYLKEYHYKSKVRVRRVDAPEQR 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SOCS4	NP_543143.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29		19/27 (70%)
		SOCS	58..111	CDD:432667	41/52 (79%)
		SH2_SOCS4	275..375	CDD:198248	93/99 (94%)
		SOCS_SOCS4	384..439	CDD:239707	45/54 (83%)
socs4	XP_031746340.1	SOCS	91..142	CDD:432667	41/50 (82%)
		SH2_SOCS4	298..398	CDD:198248	93/99 (94%)
		SOCS	407..462	CDD:470605	45/54 (83%)