Protein Alignment SOCS4 and Socs4

DIOPT Version :10

• Sequence 1: NP_543143.1
• Gene: SOCS4 / 122809
• HGNCID: 19392
• Length: 440
• Species: Homo sapiens
• Sequence 2: NP_001100726.1
• Gene: Socs4 / 305828
• RGDID: 1306503
• Length: 436
• Species: Rattus norvegicus
• Alignment Length: 439
• Identity: 373/439 - (84%)
• Similarity: 403/439 - (91%)
• Gaps: 3/439 - (0%)

Human     1 MAENNENISKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESYSDAETVNGIEKTEVSLRNQ 65
            |||||   ||||||||||||||||||||||||||||||||:||||.|::|.|..:|..|:.||:|
  Rat     1 MAENN---SKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSRKSESCSESEAVGTLESVEIPLRSQ 62

Human    66 ERKHSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPIKNCSSRHSSGLPSKRKIHISELMLD 130
            ||:.||||||||||||||||||||||||||||||||||||:||.:|||.||||||.|||||||||
  Rat    63 ERELSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPIRNCGARHSPGLPSKRTIHISELMLD 127

Human   131 KCPFPPRSDLAFRWHFIKRHTAPINSKSDEWVSTDLSQTELRDGQLKRRNMEENINCFSHTNVQP 195
            ||||||.||||||||||||||..::|.|||||||||.:...||.|||||:.|::|.|||||:|||
  Rat   128 KCPFPPPSDLAFRWHFIKRHTVALSSSSDEWVSTDLCERRPRDAQLKRRSTEDDIPCFSHTSVQP 192

Human   196 CVITTDNALCREGPMTGSVMNLVSNNSIEDSDMDSDDEILTLCTSSRKRNKPKWDLDDEILQLET 260
            |||||::|.|..|.:|||:||||::||:||.||||:|||:||||||||||||:|:.||.|||||.
  Rat   193 CVITTNSASCAGGHVTGSLMNLVTDNSMEDGDMDSEDEIITLCTSSRKRNKPRWETDDGILQLEA 257

Human   261 PPKYHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYLFSVSFR 325
            |||:|||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||
  Rat   258 PPKFHTQIDYVHCLVPDLLQISNNPCYWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYLFSVSFR 322

Human   326 RYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGLLEHYKDPSACMFFEPLLSTPLIRTFPFSLQ 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   323 RYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGLLEHYKDPSACMFFEPLLSTPLIRTFPFSLQ 387

Human   391 HICRTVICNCTTYDGIDALPIPSSMKLYLKEYHYKSKVRVLRIDAPEQQ 439
            |||||||||||||||||||||||.|||||||||||||||:||||.||.|
  Rat   388 HICRTVICNCTTYDGIDALPIPSPMKLYLKEYHYKSKVRLLRIDVPEPQ 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SOCS4	NP_543143.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29		24/27 (89%)
		SOCS	58..111	CDD:432667	44/52 (85%)
		SH2_SOCS4	275..375	CDD:198248	98/99 (99%)
		SOCS_SOCS4	384..439	CDD:239707	51/54 (94%)
Socs4	NP_001100726.1	SOCS	55..105	CDD:432667	42/49 (86%)
		SH2_SOCS4	272..372	CDD:198248	98/99 (99%)
		SOCS	381..436	CDD:470605	51/54 (94%)