Protein Alignment FRMD6 and Frmd6

DIOPT Version :10

• Sequence 1: NP_001253975.1
• Gene: FRMD6 / 122786
• HGNCID: 19839
• Length: 622
• Species: Homo sapiens
• Sequence 2: NP_082403.2
• Gene: Frmd6 / 319710
• MGIID: 2442579
• Length: 622
• Species: Mus musculus
• Alignment Length: 622
• Identity: 582/622 - (93%)
• Similarity: 601/622 - (96%)
• Gaps: 0/622 - (0%)

Human     1 MNKLNFHNNRVMQDRRSVCIFLPNDESLNIIINVKILCHQLLVQVCDLLRLKDCHLFGLSVIQNN 65
            ||||.||||:.|||||.||||||||:|::||||||||||||||||||||||||.|||||||||||
Mouse     1 MNKLTFHNNKAMQDRRRVCIFLPNDKSVSIIINVKILCHQLLVQVCDLLRLKDSHLFGLSVIQNN 65

Human    66 EHVYMELSQKLYKYCPKEWKKEASKVRQYEVTWGIDQFGPPMIIHFRVQYYVENGRLISDRAARY 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||:|||||.|||
Mouse    66 EHVYMELSQKLYKYCPKEWKKEASKVRQYEVTWGIDQFGPPMIIHFRVQYYVENGKLISDRIARY 130

Human   131 YYYWHLRKQVLHSQCVLREEAYFLLAAFALQADLGNFKRNKHYGKYFEPEAYFPSWVVSKRGKDY 195
            |||||||||||||||||||||||||||||||||||||||..|:|.|||||||||:||||||||||
Mouse   131 YYYWHLRKQVLHSQCVLREEAYFLLAAFALQADLGNFKRKLHHGDYFEPEAYFPAWVVSKRGKDY 195

Human   196 ILKHIPNMHKDQFALTASEAHLKYIKEAVRLDDVAVHYYRLYKDKREIEASLTLGLTMRGIQIFQ 260
            ||||||||||||||||||||:||||||||||||||:|||||||||||.|.|||||||||||||||
Mouse   196 ILKHIPNMHKDQFALTASEAYLKYIKEAVRLDDVAIHYYRLYKDKREAEGSLTLGLTMRGIQIFQ 260

Human   261 NLDEEKQLLYDFPWTNVGKLVFVGKKFEILPDGLPSARKLIYYTGCPMRSRHLLQLLSNSHRLYM 325
            ||:|||||||||||||||||||||||||||||||||||||:||||||.|||||||||||||||||
Mouse   261 NLEEEKQLLYDFPWTNVGKLVFVGKKFEILPDGLPSARKLVYYTGCPTRSRHLLQLLSNSHRLYM 325

Human   326 NLQPVLRHIRKLEENEEKKQYRESYISDNLDLDMDQLEKRSRASGSSAGSMKHKRLSRHSTASHS 390
            ||||||||:||.|||||||||||||||||||||||.||||||||||||||:||||||||||||||
Mouse   326 NLQPVLRHLRKQEENEEKKQYRESYISDNLDLDMDPLEKRSRASGSSAGSVKHKRLSRHSTASHS 390

Human   391 SSHTSGIEADTKPRDTGPEDSYSSSAIHRKLKTCSSMTSHGSSHTSGVESGGKDRLEEDLQDDEI 455
            |||||||||||||||.|||||.|.||:||||||||||||||||||||||||||||||||.||:||
Mouse   391 SSHTSGIEADTKPRDPGPEDSCSGSAMHRKLKTCSSMTSHGSSHTSGVESGGKDRLEEDSQDEEI 455

Human   456 EMLVDDPRDLEQMNEESLEVSPDMCIYITEDMLMSRKLNGHSGLIVKEIGSSTSSSSETVVKLRG 520
            |||||||||||.|.||||||||:||||||||||:|||||||||||||||||||||||||||:|||
Mouse   456 EMLVDDPRDLEPMPEESLEVSPEMCIYITEDMLLSRKLNGHSGLIVKEIGSSTSSSSETVVRLRG 520

Human   521 QSTDSLPQTICRKPKTSTDRHSLSLDDIRLYQKDFLRIAGLCQDTAQSYTFGCGHELDEEGLYCN 585
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.|||||
Mouse   521 QSTDSLPQTICRKPKTSTDRHSLSLDDIRLYQKDFLRIAGLCQDTAQSYTFGCGHELDESGLYCN 585

Human   586 SCLAQQCINIQDAFPVKRTSKYFSLDLTHDEVPEFVV 622
            |||||||:||||||||||.||||||||||||||||||
Mouse   586 SCLAQQCVNIQDAFPVKRASKYFSLDLTHDEVPEFVV 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FRMD6	NP_001253975.1	FERM_F1_FRMD6	15..120	CDD:340718	99/104 (95%)
		FERM_M	118..234	CDD:459788	106/115 (92%)
		FERM_C_FRMD1_FRMD6	227..335	CDD:270006	101/107 (94%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..445		75/80 (94%)
Frmd6	NP_082403.2	Ubl1_cv_Nsp3_N-like	15..120	CDD:475130	99/104 (95%)
		FERM_M	118..234	CDD:459788	106/115 (92%)
		FERM_C_FRMD1_FRMD6	227..335	CDD:270006	101/107 (94%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	357..452		87/94 (93%)